Intellectual disability, severe

Known as: Severe mental retardation, Severe mental subnormality, Severe intellectual disabilities 
Severe mental retardation is defined as an intelligence quotient (IQ) in the range of 20-34. [HPO:probinson]
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Understanding positive, as well as negative, impact of a child with mental retardation will lead to a more balanced view of… (More)
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Highly Cited
2005
Highly Cited
2005
Loss-of-function mutations of the MECP2 gene at Xq28 are associated with Rett syndrome in females and with syndromic and… (More)
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Highly Cited
2005
Highly Cited
2005
Mutations in genes encoding chromatin-remodeling proteins, such as the ATRX gene, underlie a number of genetic disorders… (More)
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Highly Cited
2003
Highly Cited
2003
The congenital muscular dystrophies (CMD) are a heterogeneous group of autosomal recessive disorders. A new pathomechanism has… (More)
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Highly Cited
2002
Highly Cited
2002
In the last few years, several genes involved in X-specific mental retardation (MR) have been identified by using genetic… (More)
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Highly Cited
2001
Highly Cited
2001
OBJECTIVE To evaluate the neurologic outcomes of neonates and infants suffering from persistent hyperinsulinemic hypoglycemia of… (More)
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Highly Cited
1999
Highly Cited
1999
In this study, we found that the E6-associated protein (E6-AP/UBE3A) directly interacts with and coactivates the transcriptional… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND This study examined the relation of neonatal cranial ultrasound abnormalities to psychiatric disorder at age 6 years… (More)
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Highly Cited
1997
Highly Cited
1997
The cerebro-hepato-renal syndrome of Zellweger is a fatal inherited disease caused by deficient import of peroxisomal matrix… (More)
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Highly Cited
1985
Highly Cited
1985
The prevalence of Rett's syndrome was studied in a part of southwestern Sweden comprising five counties and the city of… (More)
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