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Integrin alphaV

Known as: CD51 Antigens, alpha(V) Integrin, CD51 Antigen 
An alpha integrin with a molecular weight of 160-kDa that is found in a variety of cell types. It undergoes posttranslational cleavage into a heavy… 
National Institutes of Health

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ITGAV geneITGAV wt AlleleIn Bloodaspects of radiation effects

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Integrin Alpha-V, human

Papers overview

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2010
2010
Site‐specific inhibition of integrin αvβ3‐vitronectin association by a ser‐asp‐val sequence through an Arg‐Gly‐Asp‐binding site of the integrin
A functional proteomic technology using protein chip and molecular simulation was used to demonstrate a novel biomolecular… 
2010
2010
Pharmacology and placental transfer of a human alphav integrin monoclonal antibody in rabbits.
BACKGROUND Intetumumab is a human IgG1 anti-alphav-integrin monoclonal antibody that inhibits angiogenesis. Integrin binding and… 
2008
2008
Role of the αv-integrin subunit in cell proliferation, apoptosis and tumor metastasis of laryngeal and hypopharyngeal squamous cell carcinomas: a clinical and in vitro investigation
The objective of this study was to investigate the role of αv-integrin subunit (ITGAV, CD51) in invasion and metastasis of the… 
2004
2004
Quantitation and Kinetics of CD51 Surface Receptor Expression: Implications for Targeted Delivery
The CD51 integrin subunit is important in many functions ranging from mediation of adenovirus attachment and internalization to… 
2004
2004
Alpha V Integrin Prolongs Collagenase Production Through Jun Activation Binding Protein 1
Robust expression of αv integrin and matrix metalloproteinase 1 (MMP1) plays an important role in cancer metastasis and wound… 
2004
2004
Differential adhesion of metastatic RAW117 large-cell lymphoma cells under static or hydrodynamic conditions: role of integrin alpha v beta3
RGD-containing substrates were used to study static and hydrodynamic adhesion of murine RAW117 large-cell lymphoma sublines with… 
2003
2003
Membrane type-1 matrix metalloproteinase (MT1-MMP) processing of pro-alphav integrin regulates cross-talk between alphavbeta3 and alpha2beta1 integrins in breast carcinoma cells.
We have recently demonstrated that in breast carcinoma MCF7 cells MT1-MMP processes the alphav, alpha3, and alpha5 integrin… 
1995
1995
Integrin alpha v subunit is expressed on mesodermal cell surfaces during amphibian gastrulation.
Mesodermal cell migration during amphibian gastrulation is dependent on cellular interactions with fibronectin. One mechanism… 
1994
1994
Localization of thrombospondin, CD36 and CD51 during prenatal development of the human mammary gland.
Thrombospondin (TSP) is a 450 kDa extracellular matrix glycoprotein expressed in normal, hyperplastic, and neoplastic human… 
1993
1993
Binding of osteopontin to the osteoclast integrin alpha v beta 3.
Occupancy of the chicken osteoclast alpha v beta 3 integrin stimulates immediate cell signals. Peptides from osteopontin… 
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