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Insulin Receptor

Known as: Insulin Receptors, Receptor, Insulin [Chemical/Ingredient], receptor insulin 
A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor… 
National Institutes of Health

Related topics

Related topics

22 relations
Donohue SyndromeINSR geneINSR wt AlleleIn Blood

Broader (2)

Growth Factor ReceptorsReceptor Protein-Tyrosine Kinases

Narrower (5)

INSR protein, humanInsulin Receptor beta Subunitinsulin proreceptorinsulin receptor serine kinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1992
Highly Cited
1992
Effects of in vivo estrogen treatment on adipose tissue metabolism and nuclear estrogen receptor binding in isolated rat adipocytes
Highly Cited
1991
Highly Cited
1991
Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region
The effect of receptor occupancy on insulin receptor endocytosis was examined in CHO cells expressing normal human insulin… 
Highly Cited
1990
Highly Cited
1990
CD45, an integral membrane protein tyrosine phosphatase. Characterization of enzyme activity.
Highly Cited
1986
Highly Cited
1986
Localization of 125I-insulin binding sites in the rat hypothalamus by quantitative autoradiography
Highly Cited
1986
Highly Cited
1986
Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody.
A Drosophila genomic fragment has been isolated with a deduced amino acid sequence that is strikingly homologous to that of the… 
Highly Cited
1986
Highly Cited
1986
Characterization of rat liver endosomal fractions. In vivo activation of insulin-stimulable receptor kinase in these structures.
A protocol employing discontinuous sucrose gradient centrifugation was developed to prepare light mitochondrial (L) and Golgi… 
Highly Cited
1979
Highly Cited
1979
Stoichiometric binding and regulation of insulin receptors on human diploid fibroblasts using physiologic insulin levels.
Cultured diploid human fibroblasts bind insulin to specific receptors which can be regulated with physiologic levels of insulin… 
Highly Cited
1978
Highly Cited
1978
Insulin resistance, acanthosis nigricans, and normal insulin receptors in a young woman: evidence for a postreceptor defect.
We have previously described a group of young females with virilization, acanthosis nigricans, insulin resistance, and markedly… 
Highly Cited
1977
Highly Cited
1977
Biochemical basis of fat cell insulin resistance in obese rodents and man.
Highly Cited
1973
Highly Cited
1973
Insulin-like activity of concanavalin A and wheat germ agglutinin--direct interactions with insulin receptors.
Concanavalin A and wheat germ agglutinin are as effective as insulin in enhancing the rate of glucose transport and in inhibiting… 
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