Insulin-Like-Growth Factor I Receptor

Known as: Receptors, IGF-1, Receptor, IGF I, IGF-1 Receptors 
A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Insulin like growth factor-1 receptor (IGF-1R) and insulin receptor (IR) signalling control vital growth, survival and metabolic… (More)
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Highly Cited
2010
Highly Cited
2010
Insulin-like growth factor-1 receptor (IGF-1R) is a receptor tyrosine kinase (RTK) and critical activator of the… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE The insulin-like growth factor (IGF) signaling axis is frequently dysregulated in hepatocellular carcinoma (HCC… (More)
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Highly Cited
2008
Highly Cited
2008
Rather than being a passive, haphazard process of wear and tear, lifespan can be modulated actively by components of the insulin… (More)
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Highly Cited
2007
Highly Cited
2007
The insulin-like growth factor (IGF-1) signalling is highly implicated in cancer. In this signalling the IGF-1 receptor (IGF-1R… (More)
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Highly Cited
2003
Highly Cited
2003
Studies in invertebrates have led to the identification of a number of genes that regulate lifespan, some of which encode… (More)
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Review
2003
Review
2003
The type 1 insulin-like growth factor receptor (IGF-1R) plays an important role in the establishment and maintenance of the… (More)
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Review
2002
Review
2002
Interest in insulin-like growth factors (IGFs) and their effect on carcinogenesis has increased recently because high serum… (More)
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Highly Cited
2002
Highly Cited
2002
Parathyroid hormone (PTH) is a potent anabolic agent for bone, but the mechanism(s) by which it works remains imperfectly… (More)
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Highly Cited
1993
Highly Cited
1993
Wilms tumor is a pediatric neoplasm that arises from the metanephric blastema. The expression of the gene encoding insulin-like… (More)
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