Insulin-Like Growth Factor Binding Protein 2

Known as: IGF-Binding Protein 2, Insulin-Like Growth Factor Binding Protein 2 [Chemical/Ingredient], Insulin Like Growth Factor Binding Protein 2 
One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at… (More)
National Institutes of Health

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IGFBP2 geneIGFBP2 wt AlleleIn BloodInsulin-like growth factor binding protein 2 measurement
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Insulin-Like Growth Factor-Binding Protein 2, human

Papers overview

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Highly Cited
2007
Highly Cited
2007
IGF-binding protein-2 protects against the development of obesity and insulin resistance.
Proliferation of adipocyte precursors and their differentiation into mature adipocytes contributes to the development of obesity… (More)
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Highly Cited
2004
Highly Cited
2004
Elevated serum insulin-like growth factor binding protein-2 as a prognostic marker in patients with ovarian cancer.
PURPOSE The purpose of this research was to examine the diagnostic and prognostic significance of elevated serum insulin-like… (More)
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2001
2001
Evaluation of plasma insulin-like growth factor binding protein-2 as a marker for adrenocortical tumors.
OBJECTIVE Recent studies have pointed to the role of the IGF system in the pathogenesis of adrenocortical tumors, and it was… (More)
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Highly Cited
1999
Highly Cited
1999
Insulin-like growth factors (IGF-I, free IGF-I and IGF-II) and insulin-like growth factor binding proteins (IGFBP-2, IGFBP-3, IGFBP-6, and ALS) in blood circulation.
Insulin-like growth factors (IGFs) and IGF binding proteins (IGFBPs) play an important role in cell growth and differentiation… (More)
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1998
1998
Insulin-like growth factor-binding protein-5 is cleaved by physiological concentrations of thrombin.
Insulin-like growth factor (IGF)-binding protein-5 (IGFBP-5) is cleaved by a serine protease that is secreted by fibroblasts and… (More)
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Highly Cited
1997
Highly Cited
1997
Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone
OBJECTIVES: We investigated the effect of obesity on the serum levels of total and free IGF-1 and their relationship to the… (More)
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1997
1997
Characterization of truncated insulin-like growth factor-binding protein-2 in human milk.
Truncated forms of insulin-like growth factor (IGF)-binding protein-2 (IGFBP-2) have been purified from human milk and shown to… (More)
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Highly Cited
1992
Highly Cited
1992
The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins.
We studied the relationship of serum insulin-like growth factor-I (IGF-I), IGF-II, the IGF-binding proteins IGFBP-1, IGFBP-2, and… (More)
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1992
1992
Insulin-like growth factor-binding protein-3 proteolysis is induced after elective surgery.
The insulin-like growth factors (IGFs) are bound to several binding proteins (IGFBPs) that appear to regulate IGF transport… (More)
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1990
1990
Characterization of insulin-like growth factor binding proteins produced in the rat central nervous system.
Insulin-like growth factor binding proteins (IGFBP) are thought to modulate the biological actions of the insulin-like growth… (More)
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