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Insulin-Like Growth Factor Binding Protein 2

Known as: IGF-Binding Protein 2, Insulin-Like Growth Factor Binding Protein 2 [Chemical/Ingredient], Insulin Like Growth Factor Binding Protein 2 
One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at… 
National Institutes of Health

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IGFBP2 geneIGFBP2 wt AlleleIn BloodInsulin-like growth factor binding protein 2 measurement

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Insulin-Like Growth Factor-Binding Protein 2, human

Papers overview

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Highly Cited
2011
Highly Cited
2011
Evolution of the insulin-like growth factor binding protein (IGFBP) family.
The evolution of the IGF binding protein (IGFBP) gene family has been difficult to resolve. Both chromosomal and serial… 
Highly Cited
2007
Highly Cited
2007
IGF-Binding Protein-2 Protects Against the Development of Obesity and Insulin Resistance
Proliferation of adipocyte precursors and their differentiation into mature adipocytes contributes to the development of obesity… 
Highly Cited
2004
Highly Cited
2004
Elevated Serum Insulin-Like Growth Factor Binding Protein-2 as a Prognostic Marker in Patients with Ovarian Cancer
Purpose: The purpose of this research was to examine the diagnostic and prognostic significance of elevated serum insulin-like… 
Highly Cited
1999
Highly Cited
1999
Overexpression of Insulin-Like Growth Factor-Binding Protein-2 in Transgenic Mice Reduces Postnatal Body Weight Gain.
Insulin-like growth factor (IGF)-binding protein-2 (IGFBP-2) has been shown to inhibit IGF-dependent cell proliferation in a… 
Highly Cited
1997
Highly Cited
1997
Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone
OBJECTIVES: We investigated the effect of obesity on the serum levels of total and free IGF-1 and their relationship to the… 
Highly Cited
1996
Highly Cited
1996
Insulin-like growth factor I and insulin-like growth factor-binding proteins in bovine serum and follicular fluid before and after the preovulatory surge of luteinizing hormone.
Previous studies have shown that concentrations of insulin-like growth factor (IGF)-binding proteins (BPs) in bovine follicles… 
Highly Cited
1995
Highly Cited
1995
Regulation of the insulin-like growth factors and their binding proteins by glucocorticoid and growth hormone in nonislet cell tumor hypoglycemia.
Hypoglycemia in patients with nonislet cell tumors is often secondary to overexpression of tumor insulin-like growth factor (IGF… 
Highly Cited
1992
Highly Cited
1992
The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins.
We studied the relationship of serum insulin-like growth factor-I (IGF-I), IGF-II, the IGF-binding proteins IGFBP-1, IGFBP-2, and… 
Highly Cited
1992
Highly Cited
1992
Insulin-like growth factor-binding protein-3 proteolysis is induced after elective surgery.
The insulin-like growth factors (IGFs) are bound to several binding proteins (IGFBPs) that appear to regulate IGF transport… 
Highly Cited
1990
Highly Cited
1990
Characterization of insulin-like growth factor binding proteins produced in the rat central nervous system.
Insulin-like growth factor binding proteins (IGFBP) are thought to modulate the biological actions of the insulin-like growth… 
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