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Insulin-Like Growth Factor 1 Receptor Beta Chain, Human

Known as: IGF1R Beta Chain, CD221 Antigen Beta Chain, IGF-IR Beta Chain 
Insulin-like growth factor 1 receptor beta chain (627 aa, ~71 kDa) is encoded by the human IGF1R gene. This protein plays a role in growth factor… 
National Institutes of Health

Related topics

Related topics

19 relations
Cell Differentiation processCell ProliferationCell Proliferation Regulatory ProcessEnzyme Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Antagonistic Autoantibodies to Insulin-Like Growth Factor-1 Receptor Associate with Poor Physical Strength
Natural autoantibodies to the IGF1 receptor (IGF1R-aAb) have been described in relation to Graves’ ophthalmopathy. Other… 
2017
2017
Expanding Genetic and Functional Diagnoses of IGF1R Haploinsufficiencies
Background: The growth-promoting effects of IGF-I is mediated through the IGF-I receptor (IGF1R), a widely expressed cell-surface… 
2017
2017
Supplementary Material for: Expanding Genetic and Functional Diagnoses of IGF1R Haploinsufficiencies
Highly Cited
2010
Highly Cited
2010
Insulin-like growth factor axis gene polymorphisms and clinical outcomes in pancreatic cancer.
BACKGROUND & AIMS Insulin-like growth factor (IGF)-axis mediated signaling pathways play an important role in pancreatic cancer… 
Review
2009
Review
2009
Two short children born small for gestational age with insulin-like growth factor 1 receptor haploinsufficiency illustrate the heterogeneity of its phenotype.
CONTEXT Small for gestational age (SGA)-born children comprise a heterogeneous group in which only few genetic causes have been… 
2008
2008
Modification of IGF1R Expression on Malignant Lymphoid Cells by a Proteasome Inhibitor
Purpose: The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase, which is overexpressed by tumors, and mediates… 
Highly Cited
1998
Highly Cited
1998
Protein Kinase C-δ Is an Important Signaling Molecule in Insulin-Like Growth Factor I Receptor-Mediated Cell Transformation
ABSTRACT To investigate the potential role of protein kinase C-δ (PKC-δ) in insulin-like growth factor I receptor (IGF-IR… 
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