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Insulin-Like Growth Factor 1 Receptor Beta Chain, Human
Known as:
IGF1R Beta Chain
, CD221 Antigen Beta Chain
, IGF-IR Beta Chain
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Insulin-like growth factor 1 receptor beta chain (627 aa, ~71 kDa) is encoded by the human IGF1R gene. This protein plays a role in growth factor…
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National Institutes of Health
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Related topics
Related topics
19 relations
Cell Differentiation process
Cell Proliferation
Cell Proliferation Regulatory Process
Enzyme Gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Antagonistic Autoantibodies to Insulin-Like Growth Factor-1 Receptor Associate with Poor Physical Strength
C. Schwiebert
,
P. Kühnen
,
+5 authors
L. Schomburg
International Journal of Molecular Sciences
2020
Corpus ID: 210334050
Natural autoantibodies to the IGF1 receptor (IGF1R-aAb) have been described in relation to Graves’ ophthalmopathy. Other…
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2017
2017
Expanding Genetic and Functional Diagnoses of IGF1R Haploinsufficiencies
P. Ocaranza
,
M. Golekoh
,
+8 authors
V. Hwa
Hormone Research in Paediatrics
2017
Corpus ID: 4723608
Background: The growth-promoting effects of IGF-I is mediated through the IGF-I receptor (IGF1R), a widely expressed cell-surface…
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2017
2017
Supplementary Material for: Expanding Genetic and Functional Diagnoses of IGF1R Haploinsufficiencies
P. Ocaranza
,
M. Golekoh
,
+8 authors
V. Hwa
2017
Corpus ID: 79471365
Highly Cited
2010
Highly Cited
2010
Insulin-like growth factor axis gene polymorphisms and clinical outcomes in pancreatic cancer.
Xiaoqun Dong
,
M. Javle
,
K. Hess
,
R. Shroff
,
J. Abbruzzese
,
Donghui Li
Gastroenterology
2010
Corpus ID: 9605314
BACKGROUND & AIMS Insulin-like growth factor (IGF)-axis mediated signaling pathways play an important role in pancreatic cancer…
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Review
2009
Review
2009
Two short children born small for gestational age with insulin-like growth factor 1 receptor haploinsufficiency illustrate the heterogeneity of its phenotype.
W. Ester
,
H. V. van Duyvenvoorde
,
+6 authors
M. Losekoot
Journal of Clinical Endocrinology and Metabolism
2009
Corpus ID: 12590899
CONTEXT Small for gestational age (SGA)-born children comprise a heterogeneous group in which only few genetic causes have been…
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2008
2008
Modification of IGF1R Expression on Malignant Lymphoid Cells by a Proteasome Inhibitor
Y. Terui
,
Y. Mishima
,
Y. Mishima
,
K. Hatake
2008
Corpus ID: 208394779
Purpose: The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase, which is overexpressed by tumors, and mediates…
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Highly Cited
1998
Highly Cited
1998
Protein Kinase C-δ Is an Important Signaling Molecule in Insulin-Like Growth Factor I Receptor-Mediated Cell Transformation
Weiqun Li
,
Yixing Jiang
,
+5 authors
Lu-Hai Wang
Molecular and Cellular Biology
1998
Corpus ID: 37557684
ABSTRACT To investigate the potential role of protein kinase C-δ (PKC-δ) in insulin-like growth factor I receptor (IGF-IR…
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