Inducible CD4+CD25+ Regulatory T Cells

Known as: iTregs 
Inducible regulatory T-lymphocytes that express CD4, CD25 (the alpha chain of the interleukin 2 receptor) and forkhead box P3 (FOXP3), with potential… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
FOXP3-expressing T regulatory cells (Tregs) can be divided into two distinct subsets: naturally occurring Tregs (nTregs) that… (More)
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Highly Cited
2011
Highly Cited
2011
Adoptive transfer of thymus-derived natural regulatory T cells (nTregs) effectively suppresses disease in murine models of… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Protective CD4+CD25+ regulatory T cells bearing the Forkhead Foxp3 transcription factor can now be divided into three… (More)
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2010
2010
Human peripheral CD4(+)CD25(-) T cells can be induced to express Foxp3 when activated in vitro by TCR stimulation with TGF-β and… (More)
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2009
2009
Murine experimental autoimmune thyroiditis (EAT) is a model for Hashimoto's thyroiditis, an organ-specific autoimmune disease… (More)
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Review
2008
Review
2008
Foxp3(+) CD4(+) CD25(+) regulatory cell (Treg) subsets that maintain immunologic homeostasis have been considered to be a… (More)
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Highly Cited
2008
Highly Cited
2008
TGF-beta has pleiotropic effects on T cell differentiation that are determined by other cytokines in the local environment… (More)
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2008
2008
BACKGROUND The suppressive mechanism of CD4+CD25+ regulatory T cells (Tregs) is poorly understood. It is also not known how to… (More)
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Highly Cited
2007
Highly Cited
2007
Thymus-derived, naturally occurring CD4(+)CD25(+)Foxp3(+) regulatory T cells (nTregs) and Tregs induced in the periphery (iTregs… (More)
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Highly Cited
2007
Highly Cited
2007
Several strategies are being designed to test the therapeutic potential of Ag-specific regulatory T cells to prevent or treat… (More)
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