Indian Hedgehog Protein

Known as: Indian Hedgehog Homolog, Indian Hedgehog (Drosophila) Homolog, Indian Hedgehog Homolog (Drosophila) 
Indian hedgehog protein (411 aa, ~45 kDa) is encoded by the human IHH gene. This protein is involved in both bone growth patterning and morphogenesis… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Runx2, required for bone formation, is ectopically expressed in breast cancer cells. To address the mechanism by which Runx2… (More)
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Highly Cited
2008
Highly Cited
2008
Chondrocyte hypertrophy is an essential process required for endochondral bone formation. Proper regulation of chondrocyte… (More)
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Highly Cited
2002
Highly Cited
2002
Most current models propose Sonic hedgehog (Shh) as the primary determinant of anteroposterior development of amniote limbs. Shh… (More)
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Highly Cited
2001
Highly Cited
2001
A pool of stem cells that arise from the mesoderm during embryogenesis initiates hematopoiesis. However, factors that regulate… (More)
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Highly Cited
2001
Highly Cited
2001
Brachydactyly type A-1 (BDA-1; MIM 112500) is characterized by shortening or missing of the middle phalanges (Fig. 1a). It was… (More)
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Highly Cited
1999
Highly Cited
1999
The mechanisms that control cell proliferation and cell differentiation during morphogenesis of the endochondral skeleton of… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND The skin is responsible for forming a variety of epidermal structures that differ amongst vertebrates. In each case… (More)
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Highly Cited
1998
Highly Cited
1998
During hedgehog biosynthesis, autocatalytic processing produces a lipid-modified amino-terminal fragment (residues 24-197 in the… (More)
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Highly Cited
1996
Highly Cited
1996
Holoprosencephaly (HPE) is a common developmental defect of the forebrain and frequently the midface in humans, with both genetic… (More)
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Highly Cited
1996
Highly Cited
1996
Sonic hedgehog is a secreted factor regulating patterning of the anterior-posterior axis in the developing limb. The signaling… (More)
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