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Immunosenescence

The decline in the function of the IMMUNE SYSTEM during aging.
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Immunosenescence is characterized by deterioration of the immune system caused by aging which induces changes to innate and… Expand
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Review
2012
Review
2012
Components of the innate immune response, including neutrophils and macrophages, are the first line of defense against infections… Expand
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Review
2011
Review
2011
Although antiretroviral therapy for HIV infection prevents AIDS-related complications and prolongs life, it does not fully… Expand
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Highly Cited
2011
Highly Cited
2011
Although antiretroviral therapy for HIV infection prevents AIDSrelated complications and prolongs life, it does not fully restore… Expand
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Review
2009
Review
2009
The most profound consequences of immune senescence with respect to human health are the increased susceptibility to infectious… Expand
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Review
2009
Review
2009
An age-related decline in immune responses in the elderly results in greater susceptibility to infection and reduced responses to… Expand
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Review
2007
Review
2007
A large part of the aging phenotype, including immunosenescence, is explained by an imbalance between inflammatory and anti… Expand
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Review
2005
Review
2005
Morbidity and mortality due to infectious disease is greater in the elderly than in the young, at least partly because of age… Expand
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Review
2000
Review
2000
In this paper we extend the "network theory of aging," and we argue that a global reduction in the capacity to cope with a… Expand
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Review
2000
Review
2000
According to the remodeling theory of aging we proposed several years ago, the current data on human immunosenescence depicts a… Expand
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