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Immunological Synapses

Known as: supramolecular activation cluster, Synapses, Immunological, Immunological Synapse 
An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular… Expand
National Institutes of Health

Papers overview

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Review
2008
Review
2008
The natural killer (NK)-cell immunological synapse is the dynamic interface formed between an NK cell and its target cell… Expand
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Highly Cited
2007
Highly Cited
2007
T cells interacting with antigen-presenting cells (APCs) form an “immunological synapse” (IS), a bull's-eye pattern composed of a… Expand
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Highly Cited
2007
Highly Cited
2007
T helper (Th) cell activation is required for the adaptive immune response. Formation of the immunological synapse (IS) between… Expand
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Highly Cited
2006
Highly Cited
2006
This corrects the article DOI: 10.1038/nature05071 
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Highly Cited
2005
Highly Cited
2005
The immunological synapse is a specialized cell-cell junction that is defined by large-scale spatial patterns of receptors and… Expand
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Highly Cited
2004
Highly Cited
2004
A notable feature of T lymphocyte recognition on other cell surfaces is the formation of a stable mature immunological synapse… Expand
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Highly Cited
2003
Highly Cited
2003
The immunological synapse is a specialized cell-cell junction between T cell and antigen-presenting cell surfaces. It is… Expand
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Review
2002
Review
2002
Chapter summary T-cell activation requires interaction of T-cell antigen receptors with proteins of the major histocompatibility… Expand
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Highly Cited
2002
Highly Cited
2002
CD28 and CTLA-4 engagement with B7 expressed by APCs generates critical regulatory signals for T cell activation. CD28 is… Expand
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Highly Cited
2001
Highly Cited
2001
Cytotoxic T lymphocytes (CTL) rapidly destroy their targets. Here we show that although target cell death occurs within 5 min of… Expand
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