FAQ

Immunoglobulin Light Chains, Surrogate

Known as: Surrogate Light Chains, Immunoglobulin psiL Chain, Light Chains, Surrogate 
An immunolglobulin light chain-like protein composed of an IMMUNOGLOBULIN VARIABLE REGION-like peptide (such as light chain like lambda5 peptide) and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2017
01219932017

Related topics

Related topics

5 relations
In Bloodadministration & dosageaspects of radiation effectsisolation & purification analysis
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Immunoglobulin Light Chains, Surrogate
physiological aspects
In Blood
administration & dosage
aspects of radiation effects
isolation & purification analysis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
In old BALB/c mice, bone marrow pre-B cell and surrogate light chain reduction is associated with increased B cell reactivity to phosphorylcholine, but reduced T15 idiotype dominance.
In young adult BALB/c mice, antibodies to phosphorylcholine (PC) bearing the T15 (TEPC 15) idiotype confer protection against… (More)
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2013
2013
Broad feedback inhibition of pre-B-cell receptor signaling components.
During B lymphocyte development, first immunoglobulin heavy chain gene segments and then immunoglobulin light chain gene segments… (More)
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2012
2012
The Non-Ig Parts of the VpreB and l5 Proteins of the Surrogate Light Chain Play Opposite Roles in the Surface Representation of the Precursor B Cell Receptor
The VpreB and l5 proteins, together with Igm-H chains, form precursor BCRs (preBCRs). We established l5 2/2 /VpreB1 2/2 / VpreB2… (More)
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2008
2008
Combinatorial surrobody libraries.
A unique type of combinatorial protein libraries has been constructed. These libraries are based on the pre-B cell receptor (pre… (More)
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2004
2004
Surrogate Light Chain Expressing Human Peripheral B Cells Produce Self-reactive Antibodies
Human B cells that coexpress surrogate and conventional light chains (V-preB+L+) show an unusual heavy and light chain antibody… (More)
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2004
2004
Surface μ Heavy Chain Signals Down-Regulation of the V(D)J-Recombinase Machinery in the Absence of Surrogate Light Chain Components
Early B cell development is characterized by stepwise, ordered rearrangement of the immunoglobulin (Ig) heavy (HC) and light (LC… (More)
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2003
2003
Identification of a Pre-BCR Lacking Surrogate Light Chain
SLP-65-/- pre-B cells show a high proliferation rate in vitro. We have shown previously that lambda5 expression and consequently… (More)
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2001
2001
Adherent Cell Lines of a Soluble Pre-B Cell Receptor with Surrogate Light Chain-Mediated Interaction
 
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1998
1998
Cell Surface Expression Differentiation: Differential Intracellular Versus Surrogate Light Chain Production During B Cell
 
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1993
1993
A complex of glycoproteins is associated with VpreB/lambda 5 surrogate light chain on the surface of mu heavy chain-negative early precursor B cell lines
Monoclonal antibodies (mAbs) have been made specific for the pre-B cell-specific proteins VpreB and lambda 5 which together form… (More)
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