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Immunoglobulin Light Chains, Surrogate

Known as: Surrogate Light Chains, Immunoglobulin psiL Chain, Light Chains, Surrogate 
An immunolglobulin light chain-like protein composed of an IMMUNOGLOBULIN VARIABLE REGION-like peptide (such as light chain like lambda5 peptide) and… 
National Institutes of Health

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In Bloodaspects of radiation effectsphysiological aspects

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Surrogate lambda Light Chain

Papers overview

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Highly Cited
2008
Highly Cited
2008
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
Induced pluripotent stem (iPS) cells have been generated from mouse and human fibroblasts by the retroviral transduction of four… 
Highly Cited
2008
Highly Cited
2008
Interferon regulatory factors 4 and 8 induce the expression of Ikaros and Aiolos to down-regulate pre-B-cell receptor and promote cell-cycle withdrawal in pre-B-cell development.
Pre-B lymphocytes consist of 2 distinct cell populations: large pre-B and small pre-B. The large pre-B cells are newly generated… 
Highly Cited
2007
Highly Cited
2007
Coordinate and subspace optimization methods for linear least squares with non-quadratic regularization
Highly Cited
2002
Highly Cited
2002
Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering
Although preB cell-receptor (pre-BCR) formation and cell-surface expression is essential for B cell development, pre-BCR… 
Review
1999
Review
1999
Transcription Factors in Lymphocyte Development— T and B Cells Get Together
Highly Cited
1995
Highly Cited
1995
Down-regulation of RAG1 and RAG2 gene expression in preB cells after functional immunoglobulin heavy chain rearrangement.
Review
1995
Review
1995
Positive and negative selection events during B lymphopoiesis.
Highly Cited
1994
Highly Cited
1994
The expression of Vpre-B/λ5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice
Review
1993
Review
1993
The surrogate light chain in B-cell development.
Highly Cited
1993
Highly Cited
1993
A complex of glycoproteins is associated with VpreB/lambda 5 surrogate light chain on the surface of mu heavy chain-negative early precursor B cell lines
Monoclonal antibodies (mAbs) have been made specific for the pre-B cell- specific proteins VpreB and lambda 5 which together form… 
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