Immunoglobulin Fc Fragments

Known as: Fc Fragments, Fragment Crystallizable Region, Immunoglobulins, Fc 
Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc… (More)
National Institutes of Health

Papers overview

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2015
2015
IgG molecules exert both pro- and antiinflammatory effector functions based on the composition of the fragment crystallizable (Fc… (More)
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Highly Cited
2012
Highly Cited
2012
Macrophages are multifunctional immune cells that may either drive or modulate disease pathogenesis depending on their activation… (More)
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2010
2010
Yeast surface display libraries of human IgG1 Fc regions were prepared in which loop sequences at the C-terminal tip of the CH3… (More)
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Review
2009
Review
2009
High-dose intravenous immunoglobulin (IVIg) preparations are used currently for the treatment of autoimmune or inflammatory… (More)
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Highly Cited
2007
Highly Cited
2007
Removal of the fucose residue from the oligosaccharides attached to Asn297 of human immunoglobulin G1 (IgG1) results in a… (More)
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Highly Cited
1999
Highly Cited
1999
Human immunoglobulin A (IgA) is an abundant antibody that mediates immune protection at mucosal surfaces as well as in plasma… (More)
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1998
1998
The cooperative structure of Fc fragments prepared from myeloma human IgG1 was studied using scanning microcalorimetry and… (More)
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1983
1983
The IgG molecule, like all antibodies, is a glycoprotein, and with the discovery in 1959 that the rabbit IgG molecule could be… (More)
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Highly Cited
1981
Highly Cited
1981
The model of human Fc fragment was refined at 2.9-A resolution. Two different automated procedures for crystallographic… (More)
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Highly Cited
1976
Highly Cited
1976
The crystal structures of a human IgG antibody molecule Kol and a human Fc fragment have been determined at 4-Å and 3.5… (More)
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