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Immunoglobulin D

Known as: IgD, Immunoglobulin D [Chemical/Ingredient], immunoglobulin d (IgD) 
An immunoglobulin isotype (subclass). This isotype is expressed on naive B cells along with IgM. Little is known about its physiologic role.
National Institutes of Health

Related topics

Related topics

18 relations
AntibodiesIgD:MCnc:Pt:Ser:QnIgD:PrThr:Pt:Ser:OrdIgD:PrThr:Pt:Ser:Ord:Immunofixation

Narrower (4)

IgD pyroglobulinIgD2Immunoglobulin delta-Chainsmyeloma protein WIE

Broader (2)

ImmunoglobulinsImmunologic Factors

Papers overview

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Highly Cited
1987
Highly Cited
1987
Polyclonal activation of the murine immune system by a goat antibody to mouse IgD. IX. Induction of a polyclonal IgE response.
The possibility that injection of mice with an affinity-purified goat antibody to mouse IgD (GaM delta) that stimulates… 
1986
1986
Abortive activation of B lymphocytes by monoclonal anti-immunoglobulin antibodies.
Toward a better understanding of the signaling role of antigen-mIg binding in the generation of humoral immune responses, we have… 
1979
1979
Demonstration of mouse serum IgD.
Although the mouse would provide an excellent experimental model for the study of serum IgD function, previous investigations… 
Highly Cited
1978
Highly Cited
1978
Differential effect of neonatal injections of anti-mu or anti-delta antibodies on the synthesis of IgM, IgD, IgE, IgA, IgG1, IgG2a, IgG2b, and IgG2c immunoglobulin classes.
The effect of neonatally initiated injections of anti-µ or anti-δ antibodies on IgM, IgD, IgA, IgE, IgG1, IgG2a, IgG2b, and… 
Highly Cited
1977
Highly Cited
1977
B-cell tolerance. IV. Differential role of surface IgM and IgD in determining tolerance susceptibility of murine B cells
During ontogeny IgD appears later than IgM on splenocytes of neonatal mice (1) and at a time when mice develop a markedly… 
Highly Cited
1977
Highly Cited
1977
Structure and biologic functions of human IgD. XI. Identification and ontogeny of a rat lymphocyte immunoglobulin having antigenic cross-reactivity with human IgD.
Chicken anti-human IgD antiserum (anti-delta) has demonstrated an antigenically cross-reactive homologue on rat lymphocytes. IgD… 
Highly Cited
1977
Highly Cited
1977
The role of surface IgD in the response to thymic-independent antigens
An alloanti-delta antibody was prepared by immunizing C57BL/Ka mice with BALB/c spleen cells. Its specificity for delta-chain was… 
Highly Cited
1976
Highly Cited
1976
Preparation and characterisation of an antiserum to the mouse candidate for immunoglobulin D
ANALYSIS of mouse B-lymphocyte surface immunoglobulin (Ig) by isotopic labelling techniques reveals little, if any, IgA or IgG… 
Highly Cited
1975
Highly Cited
1975
Abnormal ratio of membrane immunoglobulin classes in mice with an X- linked B-lymphocyte defect
CBA/N mice have an X-linked genetic defect in B-lymphocyte function manifested by inability to make antibody responses to T… 
Highly Cited
1974
Highly Cited
1974
Candidate for immunoglobulin D present on murine B lymphocytes
ALTHOUGH the original discovery of human IgD is almost ten years old1, it is only very recently that a possible function for this…