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Immunity-Related GTPase Family M Protein

Known as: LPS-Stimulated RAW 264.7 Macrophage Protein 47 Homolog, EC 3.6.5.-, Interferon-Inducible Protein 1 
Immunity-related GTPase family M protein (181 aa, ~20 kDa) is encoded by the human IRGM gene. This protein is involved in the mediation of GTP… 
National Institutes of Health

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8 relations
AutophagosomeAutophagyEnzyme GeneGuanosine Triphosphate Phosphohydrolases

Papers overview

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2015
2015
Mice lack of LRG-47 display the attenuated outcome of infection with Schistosoma japonicum
Interferon-inducible GTPase LRG-47 (also named immune-related GTPase M, Irgm1) is a member of the p47 GTPase family that has been… 
2009
2009
Deleterious effects of minocycline after in vivo target deprivation of thalamocortical neurons in the immature, metallothionein‐deficient mouse brain
Compared with adults, immature metallothionein I and II knockout (MT−/−) mice incur greater neuronal loss and a more rapid rate… 
2007
2007
The P47 GTPase Lrg-47 Links Host Defense and HSC Proliferation.
Hematopoietic stem cells (HSCs) are largely quiescent, self-renewing cells that give rise to all adult blood lineages. They have… 
Review
2004
Review
2004
Alzheimer's disease, the neuroimmune axis, and viral infection
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