Idarubicin Hydrochloride

Known as: Hydrochloride, Idarubicin, Idarubicin HCl, Idarubicin Hydrochloride [Chemical/Ingredient] 
The hydrochloride salt of the anthracycline antineoplastic antibiotic idarubicin. Idarubicin intercalates into DNA and inhibits topoisomerase II… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2017
024619872017

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND All-trans retinoic acid (ATRA) with chemotherapy is the standard of care for acute promyelocytic leukemia (APL… (More)
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2011
2011
Mutant p53 frequently accumulates in cancer cells and promotes tumor cell invasion, as part of its gain of function. Its… (More)
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2007
2007
BACKGROUND AND OBJECTIVES The optimal post-remission treatment for elderly patients with acute myeloid leukemia (AML) is… (More)
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2001
2001
Arsenic trioxide (As2O3) effectively induces remissions in relapsed acute promyelocytic leukaemia (APL), but the safety of its… (More)
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2000
2000
For the four anthracyclines idarubicin, daunorubicin, epirubicin and doxorubicin the passive and active efflux rates in intact… (More)
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1999
1999
All-trans retinoic acid administered orally (oral ATRA) may not regularly lead to either molecular complete remissions (CRs) or… (More)
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1997
1997
Nineteen patients with high-risk myelodysplastic syndrome (MDS)/acute myeloid leukaemia (AML) received fludarabine, cytarabine… (More)
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1993
1993
Idarubicin (Ida), an analogue of daunomycin, was linked to a mouse monoclonal antibody against the B cell differentiation antigen… (More)
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1990
1990
Because of the reported high sensitivity of acute promyelocytic leukemia to daunorubicin, we treated 27 consecutive, newly… (More)
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1987
1987
We have evaluated the orally active anthracycline idarubicin at a dose of 40 mg/m2 in divided doses over 24 hours in 21… (More)
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