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Idarubicin Hydrochloride

Known as: Hydrochloride, Idarubicin, Idarubicin HCl, Idarubicin Hydrochloride [Chemical/Ingredient] 
The hydrochloride salt of the anthracycline antineoplastic antibiotic idarubicin. Idarubicin intercalates into DNA and inhibits topoisomerase II… Expand
National Institutes of Health

Papers overview

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2012
2012
Anthracycline chemotherapy remains a critical component of cancer treatment despite its established risk of cardiotoxicity. To… Expand
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2007
2007
BACKGROUND AND OBJECTIVES The optimal post-remission treatment for elderly patients with acute myeloid leukemia (AML) is… Expand
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Highly Cited
2005
Highly Cited
2005
The value of administering sequential courses of chemotherapy containing high-dose cytarabine in both induction and consolidation… Expand
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Highly Cited
2002
Highly Cited
2002
PURPOSE Patients with relapsed or refractory acute myeloid leukemia have a poor prognosis. We tested the safety and efficacy of a… Expand
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2001
2001
Arsenic trioxide (As2O3) effectively induces remissions in relapsed acute promyelocytic leukaemia (APL), but the safety of its… Expand
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2000
2000
For the four anthracyclines idarubicin, daunorubicin, epirubicin and doxorubicin the passive and active efflux rates in intact… Expand
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Highly Cited
1997
Highly Cited
1997
Nineteen patients with high-risk myelodysplastic syndrome (MDS)/acute myeloid leukaemia (AML) received fludarabine, cytarabine… Expand
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1997
1997
Acute myeloid leukaemia (AML) is predominantly a disease of the elderly but such patients are not always appropriate candidates… Expand
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1990
1990
Because of the reported high sensitivity of acute promyelocytic leukemia to daunorubicin, we treated 27 consecutive, newly… Expand
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1987
1987
We have evaluated the orally active anthracycline idarubicin at a dose of 40 mg/m2 in divided doses over 24 hours in 21… Expand
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