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ITX-5061
Known as:
ITX5061
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Phenylenediamines
Sulfonamides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1
Rachana Patel
,
J. Fleming
,
+14 authors
H. Leung
EMBO Molecular Medicine
2018
Corpus ID: 3900976
Metastatic castration‐resistant prostate cancer (mCRPC) is a lethal form of treatment‐resistant prostate cancer and poses…
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2018
2018
Sprouty 2 loss-induced IL 6 drives castration-resistant prostate cancer through scavenger receptor B 1
Rachana Patel
,
J. Fleming
,
+15 authors
H. Leung
2018
Corpus ID: 4377693
Metastatic castration-resistant prostate cancer (mCRPC) is a lethal form of treatment-resistant prostate cancer and poses…
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2016
2016
Effect of scavenger receptor class B type I antagonist ITX5061 in patients with hepatitis C virus infection undergoing liver transplantation
I. Rowe
,
D. Tully
,
+13 authors
D. Mutimer
Liver transplantation
2016
Corpus ID: 23346036
Hepatitis C virus (HCV) entry inhibitors have been hypothesized to prevent infection of the liver after transplantation. ITX5061…
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Highly Cited
2014
Highly Cited
2014
Safety and antiviral activity of the HCV entry inhibitor ITX5061 in treatment-naive HCV-infected adults: a randomized, double-blind, phase 1b study.
M. Sulkowski
,
Minhee Kang
,
+8 authors
M. Glesby
Journal of Infectious Diseases
2014
Corpus ID: 23673601
BACKGROUND Hepatitis C virus (HCV) entry involves scavenger receptor B1 (SRB1). In vitro, SRB1 inhibition by ITX5061 impedes HCV…
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Review
2014
Review
2014
Antibodies to the High-Density Lipoprotein Receptor SR-B1 Potently Inhibit Hepatitis C Virus Replication In Vivo: New Avenues for Preventing Reinfection of the Liver Following Transplantation
H. Drummer
Hepatology
2014
Corpus ID: 14500111
See Article on Page 1508 Direct-acting antivirals (DAAs), together with pegylated interferon and ribavirin, have shown great…
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2014
2014
Effect of scavenger receptor B-I antagonist, ITX5061, on early hepatitis C virus kinetics in liver transplantation: results of a phase 1b clinical trial
I. Rowe
,
M. Armstrong
,
+7 authors
D. Mutimer
The Lancet
2014
Corpus ID: 54303175
2013
2013
Hepatitis C virus kinetics after liver transplantation to study the role of a small molecule inhibitor of viral entry
I. Rowe
,
M. Armstrong
,
+5 authors
J. McKeating
The Lancet
2013
Corpus ID: 54255285
2011
2011
Hepatitis C virus entry receptor dynamics and studies of platelet actin dynamics using lifeact-gfp: a potential role for actin nodules in filopodia formation
A. Barnes
2011
Corpus ID: 80812106
Virus entry into target cells is mediated by the attachment of viral glycoproteins to cell surface receptors. Entry of the…
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Highly Cited
2009
Highly Cited
2009
Increased HDL Cholesterol and ApoA-I in Humans and Mice Treated With a Novel SR-BI Inhibitor
D. Masson
,
M. Koseki
,
+4 authors
A. Tall
Arteriosclerosis, Thrombosis and Vascular Biology
2009
Corpus ID: 31066052
Objectives—Increasing HDL levels is a potential strategy for the treatment of atherosclerosis. Methods and Results—ITX5061, a…
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