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ITPR2 protein, human

Known as: Inositol 1,4,5-Triphosphate Receptor 2, inositol 1,4,5-triphosphate receptor, type 2, human, IP3 Receptor Isoform 2 
Inositol 1,4,5-trisphosphate receptor type 2 (2701 aa, ~308 kDa) is encoded by the human ITPR2 gene. This protein plays a role in in second messenger… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
In Alzheimer's disease (AD), astrocytes undergo complex morphological and functional changes that include early atrophy, reactive… Expand
Highly Cited
2008
Highly Cited
2008
ATP enhances Ca2+ release from inositol (1,4,5)-trisphosphate receptors (InsP3R). However, the three isoforms of InsP3R are… Expand
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Highly Cited
2005
Highly Cited
2005
The type 2 inositol 1,4,5-trisphosphate receptor (InsP3R2) was identified previously as the predominant isoform in cardiac… Expand
Highly Cited
2005
Highly Cited
2005
In the accompanying article, we compared main functional properties of the three mammalian inositol 1,4,5-trisphosphate receptors… Expand
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Highly Cited
2005
Highly Cited
2005
Inositol 1,4,5-trisphosphate receptors (InsP3R) play a key role in intracellular calcium (Ca2+) signaling. Three mammalian InsP3R… Expand
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Highly Cited
2003
Highly Cited
2003
Objective—The aim of this study was to correlate the expression of InsP3R subtypes in native vascular and visceral myocytes with… Expand
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2002
2002
The inositol 1,4,5‐trisphosphate receptor (InsP3R) is a ligand‐gated Ca2+ channel responsible for the release of Ca2+ from… Expand
Highly Cited
1997
Highly Cited
1997
In oligodendrocyte processes, methacholine-evoked Ca2+ waves propagate via regions of specialized Ca2+ release kinetics (wave… Expand
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Highly Cited
1997
Highly Cited
1997
Abstract: We have examined the mechanisms that underlie Ca2+ wave propagation in cultured cortical astrocytes. Norepinephrine… Expand
Highly Cited
1993
Highly Cited
1993
The expression of inositol 1,4,5-trisphosphate receptor type 1 (InsP3R1) in the mouse central nervous system (CNS) was studied by… Expand