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ITPA gene

Known as: dJ794I6.3, INOSINE TRIPHOSPHATASE, nucleoside-triphosphate diphosphatase 
National Institutes of Health

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Related topics

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inosine triphosphatase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Management of anemia induced by triple therapy in patients with chronic hepatitis C: challenges, opportunities and recommendations.
2013
2013
Effect of gender and ITPA polymorphisms on ribavirin-induced anemia in chronic hepatitis C patients.
2012
2012
1130 THE EFFECT OF HEPATIC IMPAIRMENT ON THE PHARMACOKINETICS AND ANTIVIRAL ACTIVITY OF PSI-7977 IN HEPATITIS C INFECTED SUBJECTS TREATED FOR SEVEN DAYS
Highly Cited
2011
Highly Cited
2011
Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.
Hematologic abnormalities during current therapy with pegylated interferon and ribavirin (PEG-IFN/RBV) for chronic hepatitis C… 
Highly Cited
2011
Highly Cited
2011
A pharmacogenetics study of TPMT and ITPA genes detects a relationship with side effects and clinical response in patients with inflammatory bowel disease receiving Azathioprine.
BACKGROUND AND AIMS Pharmacogenetic studies in inflammatory bowel diseases (IBD) are mainly focused on genes involved in the… 
2010
2010
Quantitative in vitro and in vivo characterization of the human P32T mutant ITPase.
Highly Cited
2009
Highly Cited
2009
TPMT but not ITPA gene polymorphism influences the risk of azathioprine intolerance in renal transplant recipients
PurposeThiopurine drugs have to be withdrawn in 10–30% of cases due to side effects, and it has been presented that genetic… 
2007
2007
Analysis of ITPA Phenotype-Genotype Correlation in the Bulgarian Population Revealed a Novel Gene Variant in Exon 6
Mutations in the inosine triphosphate pyrophosphohydrolase (ITPA) gene causing enzyme deficiency were shown to have… 
Highly Cited
2005
Highly Cited
2005
Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency in the Japanese population.
Highly Cited
1979
Highly Cited
1979
Human inosine triphosphatase: catalytic properties and population studies.
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