ITK protein, human

Known as: ITK, Kinase EMT protein, human, IL2-Inducible T-Cell Kinase 
Tyrosine-protein kinase ITK/TSK (620 aa, ~75 kDa) is encoded by the human ITK gene. This protein is involved in tyrosine phosphorylation and immunity… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Monoclonal antibodies can block cellular interactions that negatively regulate T-cell immune responses, such as CD80/CTLA-4 and… (More)
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Highly Cited
2013
Highly Cited
2013
Given its critical role in T-cell signaling, interleukin-2-inducible kinase (ITK) is an appealing therapeutic target that can… (More)
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Highly Cited
2006
Highly Cited
2006
Active contour segmentation and its robust implementation using level set methods are well-established theoretical approaches… (More)
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Highly Cited
2006
Highly Cited
2006
Among peripheral T-cell lymphomas (PTCL), the heterogeneous category of unspecified PTCL represents the most common subtype… (More)
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Highly Cited
2005
Highly Cited
2005
The Insight Toolkit(ITK) is an open-source software toolkit for performing registra tion and segmentation. Segmentationis the… (More)
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Highly Cited
2005
Highly Cited
2005
Thoroughly designed, open-source toolkits emerge to boost progress in medical imaging. The Insight Toolkit (ITK) provides this… (More)
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Review
2004
Review
2004
A multidimensional image navigation and display software was designed for display and interpretation of large sets of… (More)
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Highly Cited
2003
Highly Cited
2003
Allergic asthma patients manifest airway inflammation and some show increases in eosinophils, T(H)2 cells, and cytokines… (More)
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Highly Cited
2002
Highly Cited
2002
We present the detailed planning and execution of the Insight Toolkit (ITK), an application programmers interface (API) for the… (More)
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Highly Cited
1994
Highly Cited
1994
T lymphocytes require two signals to be activated. The antigen-specific T-cell receptor can deliver the first signal, while… (More)
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