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ITGA2B gene

Known as: PLATELET GLYCOPROTEIN IIb, CD41B, PLATELET FIBRINOGEN RECEPTOR, ALPHA SUBUNIT 
This gene is involved in platelet aggregation.
National Institutes of Health

Related topics

Related topics

9 relations
Cell AdhesionITGA2B protein, humanLigand BindingPlatelet Membrane Glycoprotein IIb

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ITGA2B wt Allele

Papers overview

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2012
2012
Novel and recurrent mutations of ITGA2B and ITGB3 genes in Korean patients with Glanzmann thrombasthenia
Glanzmann thrombasthenia (GT) is an autosomal recessive bleeding disorder caused by defective glycoprotein, αIIb and β3, encoded… 
2012
2012
Folding and Oligomerization of the gp2b/gp3/gp4 Spike Proteins of Equine Arteritis Virus in Vitro
Equine arteritis virus (EAV) is a small, positive-stranded RNA virus. The glycoproteins gp2b, gp3 and gp4 form a heterotrimer in… 
2010
2010
Novel Homozygous Mutation (c.175delG) in Platelet Glycoprotein ITGA2B Gene as Cause of Glanzmann's Thrombasthenia Type I
Background: ITGA2B ITGB3 Patients: Methods/Results: Conclusion: ITGA2B Hintergrund: ITGA2B ITGB3 Patienten: Methoden/Ergebnisse… 
Review
2009
Review
2009
Genetic testing in the diagnostic evaluation of inherited platelet disorders.
Inherited disorders of platelets give rise to rare bleeding syndromes through defects of platelet function and/or platelet… 
2008
2008
Lack of association between aspirin responsiveness and seven candidate gene haplotypes in patients with symptomatic vascular disease
Summary We studied the effect of prophylactic aspirin (ASA) ingestion on platelet function in 463 patients with stroke, transient… 
2000
2000
Combination of a Direct Thrombin Inhibitor and a Platelet Glycoprotein IIb/IIIa Blocking Peptide Facilitates and Maintains Reperfusion of Platelet-Rich Thrombus with Alteplase
We sought to determine the efficacy of the combination of argatroban, a direct thrombin inhibitor, and G4120, a platelet… 
1998
1998
Protection of platelet glycoprotein IIb/IIIa receptor complex preserves platelet function during in vitro ventricular assisted circulation.
Platelet dysfunction probably contributes to bleeding associated with ventricular assist devices (VADs). Previous evidence… 
Review
1995
Review
1995
Novel antithrombotic therapeutics targeted against platelet glycoprotein IIb/IIIa.
Platelet aggregation is one of the best understood examples of adhesive cell-cell interactions. The platelet glycoprotein IIb… 
1991
1991
Study of the endoproteolytic cleavage of platelet glycoprotein IIb using oligonucleotide-mediated mutagenesis.
Highly Cited
1986
Highly Cited
1986
Identification of platelet glycoprotein IIb/IIIa as the major binding site for released platelet-von Willebrand factor.
We studied the effects(s) of two monoclonal antibodies, 6D1 and 10E5 (directed against platelet glycoprotein Ib [GPIb] and the… 
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