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ISG15 activating enzyme activity
Known as:
UBE1L
Â
Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond…Â
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National Institutes of Health
Topic mentions per year
Topic mentions per year
1994-2016
0
2
4
1994
2016
Related topics
Related topics
1 relation
UBA7 gene
Related mentions per year
Related mentions per year
1989-2018
1980
1990
2000
2010
2020
ISG15 activating enzyme activity
UBA7 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Different roles for two ubiquitin-like domains of ISG15 in protein modification.
Yong-Gang Chang
,
Xian-Zhong Yan
,
+4 authors
Hong-yu Hu
The Journal of biological chemistry
2008
ISG15 (interferon-stimulated gene 15) is a novel ubiquitin-like (UbL) modifier with two UbL domains in its architecture. We…Â
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2008
2008
The level of hepatitis B virus replication is not affected by protein ISG15 modification but is reduced by inhibition of UBP43 (USP18) expression.
Jung-Hwan Kim
,
J Luo
,
Dong-er Zhang
Journal of immunology
2008
Hepatitis B virus (HBV) causes both acute and chronic infection of the human liver and is associated with the development of…Â
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Highly Cited
2006
Highly Cited
2006
The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase.
Weiguo Zou
,
Dong-er Zhang
The Journal of biological chemistry
2006
The expression of the ubiquitin-like protein ISG15 and protein modification by ISG15 (ISGylation) are strongly activated by…Â
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2006
2006
Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling.
Keun Il Kim
,
Ming Yan
,
+5 authors
Dong-er Zhang
Molecular and cellular biology
2006
The expression of ubiquitin-like modifier ISG15 and its conjugation to target proteins are highly induced by interferon (IFN…Â
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2006
2006
Identification and Herc5-mediated ISGylation of novel target proteins.
Tomoharu Takeuchi
,
Satoshi Inoue
,
Hideyoshi Yokosawa
Biochemical and biophysical research…
2006
ISG15, a protein containing two ubiquitin-like domains, is an interferon-stimulated gene product that functions in antiviral…Â
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Highly Cited
2004
Highly Cited
2004
Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylation.
Keun Il Kim
,
Nadia V Giannakopoulos
,
Herbert W Virgin
,
Dong-er Zhang
Molecular and cellular biology
2004
Protein ISGylation is unique among ubiquitin-like conjugation systems in that the expression and conjugation processes are…Â
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2004
2004
Involvement of UBE1L in ISG15 conjugation during retinoid-induced differentiation of acute promyelocytic leukemia.
Ian F Pitha-Rowe
,
Bret A. Hassel
,
Ethan Dmitrovsky
The Journal of biological chemistry
2004
Acute promyelocytic leukemia (APL) cases expressing the t(15,17) product, promyelocytic leukemia (PML)/retinoic acid receptor…Â
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2002
2002
UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia.
Sutisak Kitareewan
,
Ian F Pitha-Rowe
,
+5 authors
Ethan Dmitrovsky
Proceedings of the National Academy of Sciences…
2002
All-trans-retinoic acid (RA) treatment induces remissions in acute promyelocytic leukemia (APL) cases expressing the t(15;17…Â
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Highly Cited
2001
Highly Cited
2001
Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein.
W. Yuan
,
Robert Krug
The EMBO journal
2001
Of the several hundred proteins induced by interferon (IFN) alpha/beta, the ubiquitin-like ISG15 protein is one of the most…Â
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1994
1994
A homozygous deletion in a small cell lung cancer cell line involving a 3p21 region with a marked instability in yeast artificial chromosomes.
Kenneth Yuh Yen Kok
,
Arjen van den Berg
,
+7 authors
Wynand P. P. M. van de Ven
Cancer research
1994
All types of lung carcinoma are characterized by a high frequency of loss of sequences from the short arm of chromosome 3, the…Â
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