ISG15 activating enzyme activity

Known as: UBE1L 
Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2016
02419942016

Papers overview

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2008
2008
ISG15 (interferon-stimulated gene 15) is a novel ubiquitin-like (UbL) modifier with two UbL domains in its architecture. We… (More)
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2008
2008
Hepatitis B virus (HBV) causes both acute and chronic infection of the human liver and is associated with the development of… (More)
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Highly Cited
2006
Highly Cited
2006
The expression of the ubiquitin-like protein ISG15 and protein modification by ISG15 (ISGylation) are strongly activated by… (More)
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2006
2006
The expression of ubiquitin-like modifier ISG15 and its conjugation to target proteins are highly induced by interferon (IFN… (More)
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2006
2006
ISG15, a protein containing two ubiquitin-like domains, is an interferon-stimulated gene product that functions in antiviral… (More)
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Highly Cited
2004
Highly Cited
2004
Protein ISGylation is unique among ubiquitin-like conjugation systems in that the expression and conjugation processes are… (More)
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2004
2004
Acute promyelocytic leukemia (APL) cases expressing the t(15,17) product, promyelocytic leukemia (PML)/retinoic acid receptor… (More)
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2002
2002
All-trans-retinoic acid (RA) treatment induces remissions in acute promyelocytic leukemia (APL) cases expressing the t(15;17… (More)
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Highly Cited
2001
Highly Cited
2001
Of the several hundred proteins induced by interferon (IFN) alpha/beta, the ubiquitin-like ISG15 protein is one of the most… (More)
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1994
1994
All types of lung carcinoma are characterized by a high frequency of loss of sequences from the short arm of chromosome 3, the… (More)
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