IRS4 wt Allele

Known as: IRS-4, Insulin Receptor Substrate 4 wt Allele, PY160 
Human IRS4 wild-type allele is located in the vicinity of 2q36 and is approximately 65 kb in length. This allele, which encodes insulin receptor… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2014
02419972014

Papers overview

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Highly Cited
2004
Highly Cited
2004
Insulin promotes adipocyte differentiation via a complex signaling network involving multiple insulin receptor substrates (IRSs… (More)
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2004
2004
The elevated insulin concentrations that occur in many women with polycystic ovary syndrome (PCOS) can contribute significantly… (More)
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2003
2003
IRS-2 plays a pivotal role in the control of pancreatic beta-cell growth. Here, the effect of altering IRS-2 expression levels in… (More)
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2002
2002
The insulin receptor substrates (IRSs) are key components in signaling from the insulin receptor, and consequently any proteins… (More)
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Highly Cited
2000
Highly Cited
2000
The insulin receptor substrates (IRSs) function in insulin signaling. Four members of the family, IRS-1 through IRS-4, are known… (More)
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1999
1999
The insulin receptor substrates (IRSs) are key proteins in signal transduction from the insulin receptor. Recently, we discovered… (More)
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1999
1999
The insulin receptor substrates (IRSs)-1-4 play important roles in signal transduction emanating from the insulin and insulin… (More)
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1999
1999
The insulin receptor initiates insulin action by phosphorylating multiple intracellular substrates. Previously, we have… (More)
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1998
1998
We recently cloned IRS-4, a new member of the insulin receptor substrate (IRS) family. In this study we have characterized IRS-4… (More)
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1998
1998
The closely related proto-oncogene proteins CrkII and CrkL consist of one SH2 and two SH3 domains and share 60% overall homology… (More)
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