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IRGM wt Allele

Known as: LRG47, Immunity-Related GTPase Family, M wt Allele, MGC149263 
Human IRGM wild-type allele is located in the vicinity of 5q33.1 and is approximately 2 kb in length. This allele, which encodes immunity-related… 
National Institutes of Health

Related topics

Related topics

6 relations
5q33.1AutophagyHydrolysisImmunity

Broader (1)

IRGM gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Environmental factors regulate Paneth cell phenotype and host susceptibility to intestinal inflammation in Irgm1-deficient mice
ABSTRACT Crohn's disease (CD) represents a chronic inflammatory disorder of the intestinal tract. Several susceptibility genes… 
2018
2018
Transcript profile distinguishes variability in human myogenic progenitor cell expansion capacity.
Primary human muscle progenitor cells (hMPCs) are commonly used to understand skeletal muscle biology, including the regenerative… 
2017
2017
Irgm1 is required for the inflammatory function of M1 macrophage in early experimental autoimmune encephalomyelitis
The classically activated (M1) macrophage has been shown to play an indispensable role in experimental autoimmune… 
2017
2017
[Role of immune-related GTPase M1 in cortical neurons autophagy of mice with sepsis-induced brain injury].
OBJECTIVE To investigate the role of immune-related GTPase M1 (IRGM1) in cortical neurons autophagy in mice with sepsis induced… 
2017
2017
Lack of association between IRGM1 (rs13361189), PTGER4 (rs 1373692) and CARD8 (rs 2043211) polymorphism and Behçet’s disease: A study from Turkey
Behcet’s disease (BD) is a severe in ammatory vasculitis which is very common among Turkish population. Recently, IRGM1… 
2015
2015
Mice lack of LRG-47 display the attenuated outcome of infection with Schistosoma japonicum
Interferon-inducible GTPase LRG-47 (also named immune-related GTPase M, Irgm1) is a member of the p47 GTPase family that has been… 
2013
2013
P674 Pancreatitis associated to inflammatory bowel disease (IBD): clinical and genetic patterns in children
2009
2009
Irgm1 Is a Negative Regulator of Interferon-Gamma Signaling in Hematopoietic Stem Cells.
Abstract 382 Hematopoietic stem cells (HSCs) are a self-renewing population of bone marrow cells that give rise to all of the… 
2008
2008
M2071 Innate Immune Defects in IRGM1, TLR2, and NOD2 Contribute to Crohn's Disease Risk and Severity in Ashkenazi Jews
2007
2007
The P47 GTPase Lrg-47 Links Host Defense and HSC Proliferation.
Hematopoietic stem cells (HSCs) are largely quiescent, self-renewing cells that give rise to all adult blood lineages. They have… 
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