FAQ

IRGM wt Allele

Known as: LRG47, Immunity-Related GTPase Family, M wt Allele, MGC149263 
Human IRGM wild-type allele is located in the vicinity of 5q33.1 and is approximately 2 kb in length. This allele, which encodes immunity-related… (More)

Topic mentions per year

Topic mentions per year

2005-2017
012320052017

Related topics

Related topics

6 relations
5q33.1AutophagyHydrolysisImmunity
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Broader (1)

IRGM gene

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
IRGM wt Allele
Hydrolysis
Autophagy
Immunity
IRGM gene
5q33.1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
[Role of immune-related GTPase M1 in cortical neurons autophagy of mice with sepsis-induced brain injury].
OBJECTIVE To investigate the role of immune-related GTPase M1 (IRGM1) in cortical neurons autophagy in mice with sepsis induced… (More)
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2017
2017
Villin-1 and Gelsolin Regulate Changes in Actin Dynamics That Affect Cell Survival Signaling Pathways and Intestinal Inflammation.
BACKGROUND & AIMS Cell stress signaling pathways result in phosphorylation of the eukaryotic translation initiation factor 2… (More)
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2017
2017
Irgm1 is required for the inflammatory function of M1 macrophage in early experimental autoimmune encephalomyelitis.
The classically activated (M1) macrophage has been shown to play an indispensable role in experimental autoimmune… (More)
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2015
2015
IRGM1 enhances B16 melanoma cell metastasis through PI3K-Rac1 mediated epithelial mesenchymal transition
Melanoma is one of the most aggressive skin cancers and is well known for its high metastatic rate. Studies have shown that… (More)
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2015
2015
Mechanisms of interferon-beta-induced inhibition of Toxoplasma gondii growth in murine macrophages and embryonic fibroblasts: role of immunity-related GTPase M1.
The apical complex of Toxoplasma gondii enables it to invade virtually all nucleated cells in warm-blooded animals, including… (More)
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2014
2014
Autophagy suppression by appendicitis and appendectomy protects against colitis.
BACKGROUND When done at a young age, appendicitis followed by appendectomy (AA) offers protection against ulcerative colitis… (More)
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2013
2013
IRGM1 regulates oxidized LDL uptake by macrophage via actin-dependent receptor internalization during atherosclerosis
Macrophage derived foam cells are actively involved in the initial phase of atherosclerosis. Uptake of modified lipoprotein such… (More)
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2012
2012
Immune-related GTPase M (IRGM1) regulates neuronal autophagy in a mouse model of stroke.
Autophagy is an important cellular recycling mechanism through self-digestion in responses to cellular stress such as starvation… (More)
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2011
2011
Concanavalin A/IFN-Gamma Triggers Autophagy-Related Necrotic Hepatocyte Death through IRGM1-Mediated Lysosomal Membrane Disruption
Interferon-gamma (IFN-γ), a potent Th1 cytokine with multiple biological functions, can induce autophagy to enhance the clearance… (More)
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2005
2005
Infectious disease: Forcing phagosomes to mature
 
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