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IRGM wt Allele

Known as: LRG47, Immunity-Related GTPase Family, M wt Allele, MGC149263 
Human IRGM wild-type allele is located in the vicinity of 5q33.1 and is approximately 2 kb in length. This allele, which encodes immunity-related… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Interferon-inducible GTPases of the Immunity Related GTPase (IRG) and Guanylate Binding Protein (GBP) families provide resistance… Expand
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2011
2011
An ancestral polymorphic allele of the human autophagy-related gene IRGM1 is associated with altered gene expression and a… Expand
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2010
2010
IRG are a family of IFN-regulated proteins that are critical for resistance to infection. Mouse IRG proteins are divided into GMS… Expand
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2010
2010
The interferon-γ (IFNγ)–inducible IRG proteins are a distinctive cytoplasmic GTPase family encoded by about 20 genes in the C57BL… Expand
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2009
2009
The immunity-related GTPases (IRG), also known as p47 GTPases, are a family of proteins that are tightly regulated by IFNs at the… Expand
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Highly Cited
2008
Highly Cited
2008
The role of Toll-like receptors (TLR) and MyD88 for immune responses to Mycobacterium tuberculosis (Mtb) infection remains… Expand
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Highly Cited
2008
Highly Cited
2008
Mice deficient in the interferon-γ (IFN-γ)-inducible, immunity-related GTPase Irgm1 have defective host resistance to a variety… Expand
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Highly Cited
2005
Highly Cited
2005
The cytokine gamma interferon (IFN-gamma) is critical for resistance to Toxoplasma gondii. IFN-gamma strongly activates… Expand
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Highly Cited
2005
Highly Cited
2005
IFN-γ is known to be required for host control of intracellular Trypanosoma cruzi infection in mice, although the basis of its… Expand
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1995
1995
The response of macrophages to agents such as lipopolysaccharide (LPS) and interferon (IFN) includes the transcriptional… Expand
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