IRF6 gene

Known as: VWS1, IRF-6, Interferon Regulatory Factor 6 
Interferon regulatory factor 6 (467 aa, ~53 kDa) is encoded by the human IRF6 gene. This protein plays a role in the regulation of transcription.

Topic mentions per year

Topic mentions per year

1997-2018
010203019972018

Papers overview

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Highly Cited
2011
Highly Cited
2011
Head and neck squamous cell carcinoma (HNSCC) is a common, morbid, and frequently lethal malignancy. To uncover its mutational… (More)
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2011
2011
While the pro-differentiation and tumour suppressive functions of Notch signalling in keratinocytes are well established, the… (More)
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Highly Cited
2008
Highly Cited
2008
Previously we have shown that nonsyndromic cleft lip with or without cleft palate (NSCL/P) is strongly associated with SNPs in… (More)
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2007
2007
Purpose: The interferon regulatory factor 6 (IRF6), the gene that causes van der Woude syndrome has been shown to be associated… (More)
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Highly Cited
2006
Highly Cited
2006
Transcription factor paralogs may share a common role in staged or overlapping expression in specific tissues, as in the Hox… (More)
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Highly Cited
2006
Highly Cited
2006
The epidermis is a highly organized structure, the integrity of which is central to the protection of an organism. Development… (More)
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2006
2006
Development of the lip and palate involves a complex series of events that are frequently disturbed resulting in the congenital… (More)
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2005
2005
Nonsyndromic cleft lip with or without cleft palate (NSCLP) is a common craniofacial birth defect which results in lifelong… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Cleft lip or palate (or the two in combination) is a common birth defect that results from a mixture of genetic and… (More)
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Highly Cited
2002
Highly Cited
2002
Interferon regulatory factor 6 (IRF6) belongs to a family of nine transcription factors that share a highly conserved helix–turn… (More)
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