INSR protein, human

Known as: INSR, insulin receptor, human, IR 
Insulin receptor (1382 aa, ~156 kDa) is encoded by the human INSR gene. This protein plays a role in both signal transduction and glucose homeostasis… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1974-2018
0102019742018

Papers overview

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Highly Cited
2010
Highly Cited
2010
Insulin like growth factor-1 receptor (IGF-1R) and insulin receptor (IR) signalling control vital growth, survival and metabolic… (More)
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Highly Cited
2010
Highly Cited
2010
OBJECTIVE The sites of insulin action in the central nervous system that regulate glucose metabolism and energy expenditure are… (More)
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Highly Cited
2007
Highly Cited
2007
Leptin, the adipocyte-secreted hormone that centrally regulates weight control, is known to function as an immunomodulatory… (More)
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2007
2007
Green tea has antidiabetic, antiobesity, and anti-inflammatory activities in animal models, but the molecular mechanisms of these… (More)
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Highly Cited
2004
Highly Cited
2004
IGF-IR-mediated signaling promotes survival, anchorage-independent growth, and oncogenic transformation, as well as tumor growth… (More)
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Highly Cited
2002
Highly Cited
2002
Reverse transcription (RT) followed by polymerase chain reaction (PCR) is the technique of choice for analysing mRNA in extremely… (More)
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Highly Cited
1998
Highly Cited
1998
sad et al., 1996), and CD32 (FcgRII; Stanton et al., 1992). The formation of foam cells from macrophages in the While the in vivo… (More)
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Highly Cited
1996
Highly Cited
1996
Targeted disruption of the insulin receptor gene (Insr) in the mouse was achieved using the homologous recombination approach… (More)
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1991
1991
Amino acid sequence of human C-type natriuretic peptide (CNP) has recently been deduced to be identical to those of porcine and… (More)
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Highly Cited
1983
Highly Cited
1983
Preparations of insulin receptor from cultured 3T3-L1 adipocytes and human placenta previously was found to catalyze the… (More)
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