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INSR protein, human

Known as: INSR, insulin receptor, human, IR 
Insulin receptor (1382 aa, ~156 kDa) is encoded by the human INSR gene. This protein plays a role in both signal transduction and glucose homeostasis… 
National Institutes of Health

Related topics

Related topics

28 relations

Broader (2)

CD AntigensInsulin Receptor
Carbohydrate MetabolismCell Differentiation processCell ProliferationDiabetes Mellitus

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1994
Highly Cited
1994
Absence of insulin receptor gene mutations in three insulin-resistant women with the polycystic ovary syndrome.
Highly Cited
1991
Highly Cited
1991
Distribution and characterization of immunoreactive porcine C-type natriuretic peptide.
Highly Cited
1991
Highly Cited
1991
Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region
The effect of receptor occupancy on insulin receptor endocytosis was examined in CHO cells expressing normal human insulin… 
Highly Cited
1988
Highly Cited
1988
Insulin receptors with defective tyrosine kinase inhibit normal receptor function at the level of substrate phosphorylation.
Highly Cited
1987
Highly Cited
1987
Insulin receptors in the peripheral nervous system: a structural and functional analysis
Highly Cited
1984
Highly Cited
1984
Insulin receptors in rat brain cortex. Kinetic evidence for a receptor subtype in the central nervous system
Review
1983
Review
1983
11 Insulin receptors in normal and disease states
Highly Cited
1982
Highly Cited
1982
Insulin receptors convert to a higher affinity state subsequent to hormone binding. A two-state model for the insulin receptor.
Highly Cited
1981
Highly Cited
1981
Levels of dynorphin-(1-13) immunoreactivity in rat neurointermediate pituitaries are concomitantly altered with those of leucine enkephalin and vasopressin in response to various endocrine…
The levels of dynorphin-(1-13), leucine enkephalin, beta-endorphin and vasopressin immunoreactivity (ir-DYN, ir-1-ENK, ir-beta… 
Highly Cited
1977
Highly Cited
1977
Insulin inhibition of antibody-dependent cytoxicity and insulin receptors in macrophages
INSULIN receptors have been demonstrated on various human white blood cells including monocytes1,2 granulocytes3 and cultured… 
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