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Characterization and biological roles of the peroxisome proliferator-activated receptor (PPAR) isotypes are well known in… Expand Background Several studies have identified multiple obesity-associated loci mainly in European populations. However, their… Expand Second-generation antipsychotics (SGAs), such as risperidone, clozapine and olanzapine, are the most common drug treatments for… Expand The use of atypical antipsychotics (AAPs) is associated with increasing the risk of the metabolic syndrome (MetS), which is an… Expand Through unknown mechanisms, insulin activates the sterol regulatory element-binding protein (SREBP1c) transcription factor to… Expand BACKGROUND
Overweight is a complex trait in which both environmental and genetic factors play a role.
We aimed to… Expand Objective: Obesity is considered a polygenic and multifactorial disorder and different single nucleotide polymorphisms (SNP) are… Expand OBJECTIVE
To determine whether 2 single nucleotide polymorphisms (SNPs) in the obesity genes the fat mass and obesity associated… Expand Obesity is a major public health problem with strong genetic determination; however, the genetic factors underlying obesity are… Expand Background The INSIG2 rs7566605 and PFKP rs6602024 polymorphisms have been identified as obesity gene variants in genome-wide… Expand