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ING4 gene

Known as: my036, inhibitor of growth family member 4, INHIBITOR OF GROWTH 4 
National Institutes of Health

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ING5 gene

Papers overview

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Highly Cited
2017
Highly Cited
2017
miR-423-5p contributes to a malignant phenotype and temozolomide chemoresistance in glioblastomas
Background Gliomas are based on a genetic abnormality and present with a dismal prognosis. MicroRNAs (miRNAs) are considered to… 
Review
2014
Review
2014
Wnt signaling pathway in non-small cell lung cancer.
  • D. Stewart
  • Journal of the National Cancer Institute
  • 2014
  • Corpus ID: 14298118
Wnt/β-catenin alterations are prominent in human malignancies. In non-small cell lung cancer (NSCLC), β-catenin and APC mutations… 
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Highly Cited
2011
Highly Cited
2011
Citrullination of Inhibitor of Growth 4 (ING4) by Peptidylarginine Deminase 4 (PAD4) Disrupts the Interaction between ING4 and p53*
  • Q. Guo, W. Fast
  • The Journal of Biological Chemistry
  • 2011
  • Corpus ID: 205309749
Gene expression is regulated by a number of interrelated posttranslational modifications of histones, including citrullination… 
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Highly Cited
2009
Highly Cited
2009
ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation.
Aberrations in chromatin dynamics play a fundamental role in tumorigenesis, yet relatively little is known of the molecular… 
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Highly Cited
2007
Highly Cited
2007
Curcumin induces G2/M cell cycle arrest in a p53-dependent manner and upregulates ING4 expression in human glioma
Gliomas are the most common and lethal primary tumors of the central nervous system (CNS). Despite current rigorous treatment… 
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Highly Cited
2007
Highly Cited
2007
The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF…
Angiogenesis has a critical role in the pathophysiology of multiple myeloma (MM); however, the molecular mechanisms underlying… 
Highly Cited
2005
Highly Cited
2005
The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF).
The hypoxia inducible factor (HIF) plays an important role in the progression of a number of pathophysiological processes… 
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Highly Cited
2004
Highly Cited
2004
The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
Gliomas are the most common primary tumours of the central nervous system, with nearly 15,000 diagnosed annually in the United… 
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Highly Cited
2004
Highly Cited
2004
A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer.
We have devised a screen for genes that suppress the loss of contact inhibition elicited by overexpression of the protooncogene… 
Highly Cited
2003
Highly Cited
2003
p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity.
We identified and characterized two new ING family genes, p29ING4 and p28ING5,coding for two proteins of 249 and 240 amino acids… 
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