ING4 gene

Known as: my036, inhibitor of growth family member 4, INHIBITOR OF GROWTH 4 
 
National Institutes of Health

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ING5 gene

Papers overview

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2012
2012
Enhanced radiosensitivity of non-small-cell lung cancer (NSCLC) by adenovirus-mediated ING4 gene therapy
Radiotherapy is the common treatment of choice for locally advanced lung cancer, but the radioresistance of lung cancer remains a… (More)
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2010
2010
MicroRNA-650 targets ING4 to promote gastric cancer tumorigenicity.
MicroRNAs (miRNAs) are non-coding RNAs that regulate the expression of target mRNAs. Altered expression of specific miRNAs in… (More)
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Highly Cited
2009
Highly Cited
2009
ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation.
Aberrations in chromatin dynamics play a fundamental role in tumorigenesis, yet relatively little is known of the molecular… (More)
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Highly Cited
2008
Highly Cited
2008
Role of ING4 in human melanoma cell migration, invasion and patient survival.
Inhibitor of growth (ING) 4 has been reported as a tumor suppressor and shown to diminish colony-forming efficiency, induce p53… (More)
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Highly Cited
2008
Highly Cited
2008
The ING4 tumor suppressor attenuates NF-kappaB activity at the promoters of target genes.
The NF-kappaB family mediates immune and inflammatory responses. In many cancers, NF-kappaB is constitutively activated and… (More)
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Highly Cited
2007
Highly Cited
2007
Curcumin induces G2/M cell cycle arrest in a p53-dependent manner and upregulates ING4 expression in human glioma
Gliomas are the most common and lethal primary tumors of the central nervous system (CNS). Despite current rigorous treatment… (More)
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Highly Cited
2005
Highly Cited
2005
The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF).
The hypoxia inducible factor (HIF) plays an important role in the progression of a number of pathophysiological processes… (More)
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Highly Cited
2004
Highly Cited
2004
The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
Gliomas are the most common primary tumours of the central nervous system, with nearly 15,000 diagnosed annually in the United… (More)
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Highly Cited
2004
Highly Cited
2004
A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer.
We have devised a screen for genes that suppress the loss of contact inhibition elicited by overexpression of the protooncogene… (More)
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Highly Cited
2004
Highly Cited
2004
ING4 induces G2/M cell cycle arrest and enhances the chemosensitivity to DNA-damage agents in HepG2 cells.
The known members of inhibitor of growth (ING) gene family are considered as candidate tumor suppressor genes. ING4, a novel… (More)
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