ING4 gene

Wnt/β-catenin alterations are prominent in human malignancies. In non-small cell lung cancer (NSCLC), β-catenin and APC mutations… Expand

MicroRNAs (miRNAs) are non-coding RNAs that regulate the expression of target mRNAs. Altered expression of specific miRNAs in… Expand

Aberrations in chromatin dynamics play a fundamental role in tumorigenesis, yet relatively little is known of the molecular… Expand

Gliomas are the most common and lethal primary tumors of the central nervous system (CNS). Despite current rigorous treatment… Expand

Angiogenesis has a critical role in the pathophysiology of multiple myeloma (MM); however, the molecular mechanisms underlying… Expand

The hypoxia inducible factor (HIF) plays an important role in the progression of a number of pathophysiological processes… Expand

We previously showed two members of the ING family, ING1 and ING3 as a tumor suppressor gene in head and neck cancer. Progress in… Expand

Gliomas are the most common primary tumours of the central nervous system, with nearly 15,000 diagnosed annually in the United… Expand

We have devised a screen for genes that suppress the loss of contact inhibition elicited by overexpression of the protooncogene… Expand

We identified and characterized two new ING family genes, p29ING4 and p28ING5,coding for two proteins of 249 and 240 amino acids… Expand