IMP dehydrogenase activity

Known as: inosine-5'-phosphate dehydrogenase activity, inosine monophosphate dehydrogenase activity, IMP oxidoreductase activity 
Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+. [EC:1.1.1.205]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2017
02419842017

Papers overview

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2009
2009
Mycophenolic acid (MPA) inhibits the enzyme inosine 5'-monophosphate dehydrogenase (IMPDH). Thus, the measurement of IMPDH… (More)
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2007
2007
BACKGROUND AND OBJECTIVE Inosine 5'-monophosphate dehydrogenase 2 is required for purine synthesis in activated lymphocytes… (More)
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2007
2007
Mycophenolic acid can be administered orally using mycophenolate mofetil or enteric-coated mycophenolate. In renal transplant… (More)
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2004
2004
UNLABELLED Mycophenolate mofetil (MMF), an inhibitor of inosine monophosphate dehydrogenase (IMPDH) activity, is usually… (More)
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2001
2001
BACKGROUND Mycophenolic acid is reported to provide effective immunosuppression by inhibiting inosine monophosphate dehydrogenase… (More)
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1999
1999
OBJECTIVES To study the pharmacologic activity of mycophenolate mofetil in stable kidney transplant recipients receiving… (More)
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1997
1997
Mycophenolic acid glucuronide (MPAG) inhibition kinetics were evaluated using purified recombinant human type II inosine… (More)
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1996
1996
The combination of pharmacokinetic and pharmacodynamic (measurement of the biological effect) monitoring of immunosuppressive… (More)
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1995
1995
The activity of inosine monophosphate dehydrogenase (IMPDH: EC 1.2.1.14) was measured in erythrocyte lysates using a non… (More)
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1985
1985
A rapid microassay method for the accurate measurement of the activity of inosine 5'-monophosphate dehydrogenase in crude tissue… (More)
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