IL1A protein, human

Known as: IL-1 Alpha, Interleukin-1-Alpha, Pro-Interleukin-1-Alpha 
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-1-alpha, one form of IL-1, is made mainly… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The TOR (target of rapamycin) kinase limits longevity by poorly understood mechanisms. Rapamycin suppresses the mammalian TORC1… (More)
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Highly Cited
2009
Highly Cited
2009
IL-33 is a chromatin-associated cytokine of the IL-1 family that has recently been linked to many diseases, including asthma… (More)
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Highly Cited
2007
Highly Cited
2007
Recent studies indicate that IL-1alpha functions intracellularly in pathways independent of its cell surface receptors by… (More)
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Highly Cited
2004
Highly Cited
2004
Toll-like receptor (TLR) 2 and TLR4 play a pivotal role in recognition of Candida albicans. We demonstrate that TLR2(-/-) mice… (More)
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Highly Cited
2001
Highly Cited
2001
Cachexia is a chronic state of negative energy balance and muscle wasting that is a severe complication of cancer and chronic… (More)
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Highly Cited
2000
Highly Cited
2000
Lipopolysaccharide (LPS) is lethal to animals because it activates cytokine release, causing septic shock and tissue injury… (More)
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Highly Cited
2000
Highly Cited
2000
Osteoclast differentiation factor (ODF, also called RANKL/TRANCE/OPGL) stimulates the differentiation of osteoclast progenitors… (More)
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Highly Cited
1996
Highly Cited
1996
Proteolysis of triple-helical collagen is an important step in the progression toward irreversible tissue damage in… (More)
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Highly Cited
1990
Highly Cited
1990
Plasma levels of tumour necrosis factor (TNF) were significantly higher in 178 Gambian children with uncomplicated malaria due to… (More)
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Highly Cited
1988
Highly Cited
1988
Manganous superoxide dismutase (MnSOD) scavenges potentially toxic superoxide radicals produced in the mitochondria. Tumor… (More)
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