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IL1A protein, human

Known as: IL-1 Alpha, Interleukin-1-Alpha, Pro-Interleukin-1-Alpha 
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-1-alpha, one form of IL-1, is made mainly… 
National Institutes of Health

Related topics

Related topics

26 relations
ApoptosisCell Proliferation Regulatory ProcessCytokine GeneCytokine Network Pathway

Broader (1)

Interleukin-1 alpha

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
Interleukin-1 (IL-1) Pathway
IL-1α and IL-1β orchestrate the proinflammatory response by multiple tightly controlled mechanisms. The interleukin-1 (IL-1… 
Highly Cited
2008
Highly Cited
2008
The IL-1-Like Cytokine IL-33 Is Constitutively Expressed in the Nucleus of Endothelial Cells and Epithelial Cells In Vivo: A Novel ‘Alarmin’?
Background Interleukin-33 (IL-33) is an IL-1-like cytokine ligand for the IL-1 receptor-related protein ST2, that activates mast… 
Highly Cited
2007
Highly Cited
2007
IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo
Recent studies indicate that IL-1α functions intracellularly in pathways independent of its cell surface receptors by… 
Highly Cited
2001
Highly Cited
2001
Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1.
Highly Cited
2000
Highly Cited
2000
High Mobility Group 1 Protein (Hmg-1) Stimulates Proinflammatory Cytokine Synthesis in Human Monocytes
Lipopolysaccharide (LPS) is lethal to animals because it activates cytokine release, causing septic shock and tissue injury… 
Highly Cited
1996
Highly Cited
1996
Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage.
Proteolysis of triple-helical collagen is an important step in the progression toward irreversible tissue damage in… 
Highly Cited
1995
Highly Cited
1995
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme.
The interleukin-1 beta (IL-1 beta) converting enzyme (ICE) processes the inactive IL-1 beta precursor to the proinflammatory… 
Highly Cited
1991
Highly Cited
1991
Dysregulation of in vitro cytokine production by monocytes during sepsis.
The production by monocytes of interleukin-1 alpha (IL-1 alpha), interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), and tumor… 
Highly Cited
1990
Highly Cited
1990
TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria
Highly Cited
1988
Highly Cited
1988
Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism
Manganous superoxide dismutase (MnSOD) scavenges potentially toxic superoxide radicals produced in the mitochondria. Tumor… 
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