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IL13RA2 wt Allele

Known as: CD213a2, IL-13R, IL13BP 
Human IL13RA2 wild-type allele is located within Xq13.1-q28 and is approximately 16 kb in length. This allele, which encodes interleukin-13 receptor… 
National Institutes of Health

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Cytokine Signaling ProcessIntercellular Communication ProcessInterleukin Signaling ProcessLigand Binding
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Papers overview

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2014
2014
Novel cancer-testis antigen expression on glioma cell lines derived from high-grade glioma patients.
Glioblastoma multiforme (GBM) is one of the most malignant and aggressive tumors, and has a very poor prognosis with a mean… 
2013
2013
New Agents for Targeting of IL-13RA2 Expressed in Primary Human and Canine Brain Tumors
Interleukin 13 receptor alpha 2 (IL-13RA2) is over-expressed in a vast majority of human patients with high-grade astrocytomas… 
Review
2012
Review
2012
Toxin-Based Targeted Therapy for Malignant Brain Tumors
Despite advances in conventional treatment modalities for malignant brain tumors—surgery, radiotherapy, and chemotherapy—the… 
2003
2003
Molecular cloning and identification of the human interleukin 13 alpha 2 receptor (IL-13Ra2) promoter.
The interleukin 13 alpha 2 receptor (IL-13Ra2) has been shown to be expressed in most malignant glioblastoma cells. Recent… 
2003
2003
Identification and characterization of interleukin-13 receptor in human medulloblastoma and targeting these receptors with interleukin-13-pseudomonas exotoxin fusion protein.
AIM To identify and characterize the subunit structure of interleukin-13 receptor (IL-13R) in human medulloblastoma cell lines… 
Highly Cited
2002
Highly Cited
2002
Heterogeneity in interleukin-13 receptor expression and subunit structure in squamous cell carcinoma of head and neck: differential sensitivity to chimeric fusion proteins comprised of interleukin-13…
Squamous cell carcinoma of the head and neck (SCCHN) is characterized by a high proliferation index and marked propensity for… 
Highly Cited
2002
Highly Cited
2002
A Novel Mechanism by Which Interferon-γ Can Regulate Interleukin (IL)-13 Responses
Interleukin (IL)-13 mediates its activities via a complex receptor system. Interleukin-13 receptor α-1 chain (IL-13Rα1) binds IL… 
2002
2002
Identification of a Novel HLA-A * 0201-restricted , Cytotoxic T Lymphocyte Epitope in a Human Glioma-associated Antigen , Interleukin 13 Receptor 2 Chain 1
Purpose: Interleukin 13 receptor 2-chain (IL-13R 2) has been reported to be abundantly and specifically overexpressed in… 
Highly Cited
1999
Highly Cited
1999
Receptor for interleukin 13 is abundantly and specifically over-expressed in patients with glioblastoma multiforme.
We have recently documented that the vast majority of patients with glioblastoma multiforme (GBM) over-express a receptor (R) for… 
Highly Cited
1996
Highly Cited
1996
IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling.
We have recently reported that IL-13R may share a component with IL-4R. Here we report that both IL-4 and IL-13 share signaling… 
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