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IL13RA2 wt Allele

Known as: CD213a2, IL-13R, IL13BP 
Human IL13RA2 wild-type allele is located within Xq13.1-q28 and is approximately 16 kb in length. This allele, which encodes interleukin-13 receptor… Expand
National Institutes of Health

Related topics

Related topics

5 relations
Cytokine Signaling ProcessIntercellular Communication ProcessInterleukin Signaling ProcessLigand Binding
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Papers overview

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2014
2014
Novel cancer-testis antigen expression on glioma cell lines derived from high-grade glioma patients.
Glioblastoma multiforme (GBM) is one of the most malignant and aggressive tumors, and has a very poor prognosis with a mean… Expand
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2013
2013
New Agents for Targeting of IL-13RA2 Expressed in Primary Human and Canine Brain Tumors
Interleukin 13 receptor alpha 2 (IL-13RA2) is over-expressed in a vast majority of human patients with high-grade astrocytomas… Expand
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Review
2012
Review
2012
Toxin-Based Targeted Therapy for Malignant Brain Tumors
Despite advances in conventional treatment modalities for malignant brain tumors—surgery, radiotherapy, and chemotherapy—the… Expand
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2003
2003
Molecular cloning and identification of the human interleukin 13 alpha 2 receptor (IL-13Ra2) promoter.
The interleukin 13 alpha 2 receptor (IL-13Ra2) has been shown to be expressed in most malignant glioblastoma cells. Recent… Expand
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2002
2002
Heterogeneity in interleukin-13 receptor expression and subunit structure in squamous cell carcinoma of head and neck: differential sensitivity to chimeric fusion proteins comprised of interleukin-13…
Squamous cell carcinoma of the head and neck (SCCHN) is characterized by a high proliferation index and marked propensity for… Expand
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2002
2002
Identification of a Novel HLA-A * 0201-restricted , Cytotoxic T Lymphocyte Epitope in a Human Glioma-associated Antigen , Interleukin 13 Receptor 2 Chain 1
Purpose: Interleukin 13 receptor 2-chain (IL-13R 2) has been reported to be abundantly and specifically overexpressed in… Expand
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2002
2002
IL-13 R 2 is a Glioma-Restricted Receptor for Interleukin-131
We have found that binding sites for interleukin-13 ( IL13) are overexpressed in a vast majority of high-grade astrocytomas (HGAs… Expand
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2002
2002
A Novel Mechanism by Which Interferon-γ Can Regulate Interleukin (IL)-13 Responses EVIDENCE FOR INTRACELLULAR STORES OF IL-13 RECEPTOR α-2 AND THEIR RAPID MOBILIZATION BY INTERFERON-γ
Abstract Interleukin (IL)-13 mediates its activities via a complex receptor system. Interleukin-13 receptor α-1 chain (IL-13Rα1… Expand
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1999
1999
Receptor for interleukin 13 is abundantly and specifically over-expressed in patients with glioblastoma multiforme.
We have recently documented that the vast majority of patients with glioblastoma multiforme (GBM) over-express a receptor (R) for… Expand
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Highly Cited
1996
Highly Cited
1996
IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling.
We have recently reported that IL-13R may share a component with IL-4R. Here we report that both IL-4 and IL-13 share signaling… Expand
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