IGF1R wt Allele

Known as: IGFIR, JTK13, Insulin Like Growth Factor 1 Receptor wt Allele 
Human IGF1R wild-type allele is located in the vicinity of 15q26.3 and is approximately 309 kb in length. This allele, which encodes insulin-like… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2016
024619902016

Papers overview

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2010
2010
Antiangiogenic treatment activity has been reported in solitary fibrous tumor (SFT), a rare and little chemosensitive sarcoma. We… (More)
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2010
2010
The insulin-like growth factor I receptor (IGFIR) has emerged as a key therapeutic target in many human malignancies, including… (More)
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Highly Cited
2008
Highly Cited
2008
Although some cancers are initially sensitive to EGFR tyrosine kinase inhibitors (TKIs), resistance invariably develops. We… (More)
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2008
2008
The insulin-like growth factor I receptor (IGFIR) and HER2 display important signaling interactions in breast cancer. We examined… (More)
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2006
2006
Most Wilms' tumors are of low stage, favorable histology, and have a high likelihood of cure with current multimodal therapy… (More)
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2000
2000
SOCS proteins are a class of proteins that are negative regulators of cytokine receptor signaling via the Janus kinase (JAK… (More)
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1998
1998
Growth plate cartilage cell express receptors for, and are affected by both IGF-I and 1 alpha, 25(OH)2D3. The studies were… (More)
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1997
1997
The 14-3-3 proteins have been implicated as potential regulators of diverse signaling pathways. Here, using two-hybrid assays and… (More)
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1997
1997
We have used a yeast two-hybrid system to identify proteins which bind to the cytosolic portion of the type 1 insulin-like growth… (More)
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1996
1996
We have used the yeast two-hybrid system to study the interaction between the IGF-I receptor and two putative substrates, IRS-1… (More)
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