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IFT88 gene

Known as: hTg737, TTC10, polaris homolog 
This gene is involved in cilium morphology and autophagy.
National Institutes of Health

Related topics

Related topics

3 relations
AutophagyCell Surface ExtensionsIFT88 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Disruption of endothelial cell intraflagellar transport protein 88 exacerbates doxorubicin-induced cardiotoxicity.
2019
2019
Primary cilia and the exocyst are linked to urinary extracellular vesicle production and content
The recently proposed idea of “urocrine signaling” hypothesizes that small secreted extracellular vesicles (EVs) contain proteins… 
2017
2017
Tg737 acts as a key driver of invasion and migration in liver cancer stem cells and correlates with poor prognosis in patients with hepatocellular carcinoma
2017
2017
Diatom flagellar genes and their expression during sexual reproduction in Leptocylindrus danicus
Flagella have been lost in the vegetative phase of the diatom life cycle, but they are still present in male gametes of centric… 
2016
2016
Separate Perceptual and Neural Processing of Velocity- and Disparity-Based 3D Motion Signals
Although the visual system uses both velocity- and disparity-based binocular information for computing 3D motion, it is unknown… 
2016
2016
Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function
Zfp423 encodes a 30-zinc finger transcription factor that intersects several canonical signaling pathways. Zfp423 mutations… 
2014
2014
Evaluating the Role of PTH in Promotion of Chondrosarcoma Cell Proliferation and Invasion by Inhibiting Primary Cilia Expression
Chondrosarcoma is characterized by secretion of a cartilage-like matrix, with high proliferation ability and metastatic potential… 
2007
2007
Combined translocation with ZNF198-FGFR1 gene fusion and deletion of potential tumor suppressors in a myeloproliferative disorder.
2005
2005
Primary cilia of inv/inv mouse renal epithelial cells sense physiological fluid flow: bending of primary cilia and Ca2+ influx.
Primary cilia are hypothesized to act as a mechanical sensor to detect renal tubular fluid flow. Anomalous structure of primary… 
2001
2001
Phenotypic variations of orpk mutation and chromosomal localization of modifiers influencing kidney phenotype.
The Oak Ridge polycystic kidney (orpk) mutant mouse model resulted from a transgene insertion into the Tg737 gene and exhibits a… 
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