IFT88 gene

Known as: hTg737, TTC10, polaris homolog 
This gene is involved in cilium morphology and autophagy.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Cilia dysfunction has long been associated with cyst formation and ciliopathies. More recently, misoriented cell division has… (More)
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Highly Cited
2009
Highly Cited
2009
The primary cilium plays a key role in the development of mammals and in the maintenance of health. Primary cilia are assembled… (More)
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Highly Cited
2005
Highly Cited
2005
Intraflagellar transport (IFT) is an active event in which cargo is transported along microtubules by motor proteins such as… (More)
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Highly Cited
2005
Highly Cited
2005
Intraflagellar transport (IFT) proteins are essential for cilia assembly and have recently been associated with a number of… (More)
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Highly Cited
2003
Highly Cited
2003
Intraflagellar transport (IFT) proteins were first identified as essential factors for the growth and maintenance of flagella in… (More)
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Highly Cited
2002
Highly Cited
2002
Approximately 10% of the photoreceptor outer segment (OS) is turned over each day, requiring large amounts of lipid and protein… (More)
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Highly Cited
2002
Highly Cited
2002
Recent evidence has suggested an association between structural and/or functional defects in the primary apical cilium of… (More)
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Highly Cited
2002
Highly Cited
2002
Defects in the PKD1 and PKD2 genes cause autosomal dominant polycystic kidney disease (PKD) in ~1 in 1000 adults worldwide. These… (More)
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Highly Cited
2000
Highly Cited
2000
Intraflagellar transport (IFT) is a rapid movement of multi-subunit protein particles along flagellar microtubules and is… (More)
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Highly Cited
2000
Highly Cited
2000
Analysis of several mutations in the mouse is providing useful insights into the nature of the genes required for the… (More)
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