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IFNL2 gene

Known as: interferon, lambda 2, IL-28A, Interferon, Lambda 2 Gene 
This gene is involved in both immunomodulation and antiviral responses.
National Institutes of Health

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8 relations
Antiviral ResponseCytokine Receptor BindingCytokine SignalingIFNL1 gene

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IFNL2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Hypothiocyanous Acid Suppresses PolyI:C-Induced Antiviral Responses by Modulating IRF3 Phosphorylation in Human Airway Epithelial Cells.
Pattern recognition receptors recognize RNA viruses and trigger type I and III interferon (IFN) production and apoptosis to limit… 
2017
2017
Interference of retroviral envelope with vaccine-induced CD8+ T cell responses is relieved by co-administration of cytokine-encoding vectors
Retroviral envelope (Env) proteins are known to exhibit immunosuppressive properties, which become apparent not only in… 
2017
2017
Association of genes of different functional classes with type 1 diabetes
The genetic structure of susceptibility to type 1 diabetes (T1D) in the population of Tomsk was studied. We had a group of T1D… 
2015
2015
IFNL3 Genotype is associated with Differential Induction of IFNL3 in Primary Human Hepatocytes
Background Lambda interferons (IFNLs) have potent antiviral activity against HCV, and polymorphisms within the IFNL gene cluster… 
2015
2015
Hepatic Interferon-λ3 (IFNL3) Gene Expression Reveals Not to Be Attenuated in Non-Favorable IFNL3 rs4803217 or IFNL4 rs368234815 Minor Allele Carriers in Chronic Hepatitis C
Genetic polymorphisms in the region of the interferon-λ genes (IFNL) associate with clearance of hepatitis C virus (HCV… 
2014
2014
Genetic polymorphisms of the IFNλ genes are associated with biochemical features in Han Chinese with HCV infection from Yunnan Province, China.
2012
2012
Sequence Analysis of the IL28A/IL28B Inverted Gene Duplication That Contains Polymorphisms Associated with Treatment Response in Hepatitis C Patients
Several SNPs located in or around the IL28B gene are associated with response of patients infected with Hepatitis C virus to… 
2011
2011
Reply to Krämer et al.: Human natural killer (NK) cell inhibition by IL28A
Following our PNAS paper linking type 3 IFN and NK cells (1), Kramer et al. have performed experiments in which they find low… 
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