IDH1 NP_005887.2:p.R132H

Known as: NP_005887.2:p.Arg132His, IDH1 NP_005887.2:p.Arg132His, Isocitrate Dehydrogenase [NADP] Cytoplasmic Arg132His 
A change in the amino acid residue at position 132 in the isocitrate dehydrogenase [NADP] cytoplasmic protein where arginine has been replaced by… (More)
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
PURPOSE The AVAglio (Avastin in Glioblastoma) and RTOG-0825 randomized, placebo-controlled phase III trials in newly diagnosed… (More)
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Highly Cited
2013
Highly Cited
2013
Mutations in IDH1 and IDH2, the genes coding for isocitrate dehydrogenases 1 and 2, are common in several human cancers… (More)
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Highly Cited
2012
Highly Cited
2012
Mutations in cytosolic isocitrate dehydrogenase 1 (IDH1) or its mitochondrial homolog IDH2 can lead to R(−)-2-hydroxyglutarate… (More)
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Highly Cited
2011
Highly Cited
2011
Somatic mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 occur in gliomas and acute myeloid leukaemia (AML). Since… (More)
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Highly Cited
2011
Highly Cited
2011
Ollier disease and Maffucci syndrome are non-hereditary skeletal disorders characterized by multiple enchondromas (Ollier disease… (More)
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Highly Cited
2010
Highly Cited
2010
Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2), are present in most gliomas and secondary glioblastomas, but are rare in… (More)
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Highly Cited
2010
Highly Cited
2010
PURPOSE We assessed the prognostic impact of IDH1 R132 mutations and a known single nucleotide polymorphism (SNP) located in the… (More)
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Highly Cited
2010
Highly Cited
2010
In the present study, DNA from 27 grade I and grade II pediatric gliomas, including ganglioglioma, desmoplastic infantile… (More)
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Highly Cited
2010
Highly Cited
2010
Somatic mutations in the isocitrate dehydrogenase 1 gene (IDH1) occur at high frequency in gliomas and seem to be a prognostic… (More)
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Highly Cited
2009
Highly Cited
2009
IDH1 R132H mutations occur in approximately 70% of astrocytomas and oligodendroglial tumors. We developed a mouse monoclonal… (More)
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