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ICRF 154
Known as:
ICRF-154
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
A Three-Dimensional Quantitative Structure-Activity Analysis of a New Class of Bisphenol Topoisomerase IIα Inhibitors
Hong Liang
,
Xing Wu
,
J. Yalowich
,
B. Hasinoff
Molecular Pharmacology
2008
Corpus ID: 32101889
After the identification of a new lead bisphenol compound that had good topoisomerase IIα (EC 5.99.1.3) inhibitory activity, a…
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2002
2002
The catalytic DNA topoisomerase II inhibitor ICRF-193 and all-trans retinoic acid cooperatively induce granulocytic differentiation of acute promyelocytic leukemia cells: candidate drugs for chemo…
N. Niitsu
,
M. Higashihara
,
Y. Honma
Experimental Hematology
2002
Corpus ID: 8429846
Highly Cited
2001
Highly Cited
2001
The catalytic DNA topoisomerase II inhibitor dexrazoxane (ICRF-187) induces differentiation and apoptosis in human leukemia K562 cells.
B. Hasinoff
,
M. Abram
,
N. Barnabé
,
T. Khélifa
,
W. Allan
,
J. Yalowich
Molecular Pharmacology
2001
Corpus ID: 19239607
The bisdioxopiperazines ICRF-187 (dexrazoxane), ICRF-193, and ICRF-154 are catalytic noncleavable complex-forming inhibitors of…
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1997
1997
Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II.
B. Hasinoff
,
T. Kuschak
,
+4 authors
J. Yalowich
Biochemical Pharmacology
1997
Corpus ID: 45300556
1997
1997
Comparison of the protective effects against chronic doxorubicin cardiotoxicity and the rates of iron (III) displacement reactions of ICRF-187 and other bisdiketopiperazines
E. Herman
,
J. Zhang
,
B. Hasinoff
,
D. Chadwick
,
J. R. Clark Jr.
,
V. Ferrans
Cancer Chemotherapy and Pharmacology
1997
Corpus ID: 36782172
Histologic and biochemical studies were carried out to compare the protective activity of various bisdiketopiperazines against…
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Highly Cited
1995
Highly Cited
1995
A QSAR study comparing the cytotoxicity and DNA topoisomerase II inhibitory effects of bisdioxopiperazine analogs of ICRF-187 (dexrazoxane).
B. Hasinoff
,
T. Kuschak
,
J. Yalowich
,
A. Creighton
Biochemical Pharmacology
1995
Corpus ID: 10562845
1992
1992
The effects of ICRF-154 in combination with other anticancer agents in vitro.
Y. Kano
,
T. Narita
,
+4 authors
Y. Miura
British Journal of Cancer
1992
Corpus ID: 16957290
We studied the effects of ICRF-154 in combination with 11 anticancer agents on four human leukaemia cell lines. Cells were…
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Highly Cited
1991
Highly Cited
1991
Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives.
K. Tanabe
,
Y. Ikegami
,
R. Ishida
,
T. Andoh
Cancer Research
1991
Corpus ID: 24879780
Several recently developed derivatives of bis(2,6-dioxopiperazine) have been shown to be new antitumor agents and are currently…
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Highly Cited
1991
Highly Cited
1991
Inhibition of intracellular topoisomerase II by antitumor bis(2,6-dioxopiperazine) derivatives: mode of cell growth inhibition distinct from that of cleavable complex-forming type inhibitors.
R. Ishida
,
T. Miki
,
+5 authors
T. Andoh
Cancer Research
1991
Corpus ID: 25155771
In the accompanying paper (K. Tanabe, Y. Ikegami, R. Ishida, and T. Andoh, Cancer Res., 51: 4903-4908, 1991), we showed that ICRF…
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1985
1985
Comparison of the protective effect of ICRF-187 and structurally related analogues against acute daunorubicin toxicity in Syrian golden hamsters.
E. Herman
,
A. el-Hage
,
A. Creighton
,
D. Witiak
,
V. Ferrans
Research communications in chemical pathology and…
1985
Corpus ID: 38637637
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