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ICI 199441

Known as: ICI 199,441, ICI-199441 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Pyrrolidines

Papers overview

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2018
2018
Allosterism within δ Opioid–κ Opioid Receptor Heteromers in Peripheral Sensory Neurons: Regulation of κ Opioid Agonist Efficacy
There is abundant evidence for formation of G protein-coupled receptor heteromers in heterologous expression systems, but little… Expand
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2015
2015
Prospects of Using of κ-Opioid Receptor Agonists U-50,488 and ICI 199,441 for Improving Heart Resistance to Ischemia/Reperfusion
We studied the ability of the agonist of κ1-opioid receptors U-50,488 in doses of 0.1 and 1 mg/kg to simulate ischemic pre- and… Expand
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2009
2009
The Effect of &kgr;-Opioid Receptor Agonists on Tetrodotoxin-Resistant Sodium Channels in Primary Sensory Neurons
BACKGROUND: A non-opioid receptor-mediated inhibition of sodium channels in dorsal root ganglia (DRGs) by &kgr;-opioid receptor… Expand
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2008
2008
LPK-26, a novel kappa-opioid receptor agonist with potent antinociceptive effects and low dependence potential.
  • Y. Tao, Q. Li, +6 authors J. Liu
  • European journal of pharmacology
  • 2008
    • Corpus ID: 12594235
Analgesics such as morphine cause many side effects including addiction, but kappa-opioid receptor agonist can produce… Expand
2008
2008
Opioid modulation of ferret vagal afferent mechanosensitivity.
Despite universal use of opioids in the clinic to inhibit pain, there is relatively little known of their peripheral actions on… Expand
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2004
2004
Differential properties between TRK-820 and U-50,488H on the discriminative stimulus effects in rats.
It has been demonstrated that the newly synthesized kappa-opioid receptor agonist TRK-820, which has a unique structure that is… Expand
2003
2003
Modulation of Myofilament Ca2+ Sensitivity by &dgr;- and &kgr;-Opioid Agonists in Intact Guinea Pig Hearts
We investigated whether &dgr;- and &kgr;-opioid agonists alter myocardial function, intracellular Ca2+ concentration ([Ca2+]i… Expand
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2000
2000
Characterization of the antinociceptive effects of TRK-820 in the rat.
We have already reported that TRK-820, (-)-17-cyclopropylmethyl-3, 14b-dihydroxy-4, 5a-epoxy-6b-[N-methyl-trans-3-(3-furyl… Expand
2000
2000
Arylacetamides as peripherally restricted kappa opioid receptor agonists.
Analogues of the kappa (kappa) opioid receptor agonist, ICI 199441, were prepared. Ki values for these analogues at the cloned… Expand
1996
1996
Aspartic acid conjugates of 2-(3,4-dichlorophenyl)-N-methyl-N-[(1S)-1(3-aminophenyl)-2-(1-pyrrolidi nyl) ethyl]acetamide: kappa opioid receptor agonists with limited access to the central nervous…
Aspartic acid conjugates of 2-(3,4-dichlorophenyl)-N-methyl-N-[(1S)-1-(3-aminophenyl)-2-(1-pyrrol idinyl) ethyl]acetamide (5… Expand
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