IC 86621

Known as: IC-86621, IC86621 
 
National Institutes of Health

Papers overview

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2013
2013
The presence of tumour hypoxia, regions of low levels of oxygen, is a distinct and exploitable feature of the solid tumour… (More)
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2012
2012
BackgroundTelomeres, the physical ends of chromosomes, play an important role in preserving genomic integrity. This protection is… (More)
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2012
2012
An improved synthesis of DNA-dependent protein kinase inhibitor, IC86621 is described. This developed method provides an easy… (More)
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2010
2010
DNA-dependent protein kinase (DNA-PK) is a key non-homologous-end-joining (NHEJ) nuclear serine/threonine protein kinase involved… (More)
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2010
2010
BackgroundRepair of DNA double strand breaks by non-homologous end joining (NHEJ) requires several proteins including Ku, DNA… (More)
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2010
2010
Background: Repair of DNA double strand breaks by non-homologous end joining (NHEJ) requires several proteins including Ku, DNA… (More)
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2009
2009
Long-term neurological deficiencies resulting from hippocampal cytotoxicity induced by cranial irradiation (IR) present a… (More)
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2004
2004
The kinase activity of DNA-dependent protein kinase (DNA-PK) is required for efficient repair of DNA double-strand breaks (DSB… (More)
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Highly Cited
2003
Highly Cited
2003
DNA-dependent protein kinase (DNA-PK), composed of Ku70, Ku80, and the catalytic subunit (DNA-PKcs), is involved in double-strand… (More)
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