Hypoxia-Inducible Factor Pathway
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The hypoxia-inducible transcription factor (HIF) co-ordinates the response of tumours to low oxygen by stimulating genes involved… Expand Research into the mechanisms of human adaptation to the hypoxic environment of high altitude is of great interest to the fields… Expand BACKGROUND
Venous hypoxia has been postulated to contribute to varicose vein (VV) formation. Direct measurements of vein wall… Expand Background: Segmental bone loss remains a challenging clinical problem.A frequent mitigating factor is inadequate blood supply… Expand Muscle regeneration involves the coordination of myogenesis and revascularization to restore proper muscle function. Myogenesis… Expand Hypoxia-inducible factor (HIF) plays an important role in cell survival by regulating iron, antioxidant defense, and… Expand The transcription factor complex hypoxia-inducible factor (HIF)-1 controls the expression of most genes involved in adaptation to… Expand Purpose of review To provide an overview of the recent advances in the understanding of the molecular mechanisms governing the… Expand Much of the interest in angiogenesis and hypoxia has led to investigating diagnostic imaging methodologies and developing… Expand Homeostasis under hypoxic conditions is maintained through a coordinated transcriptional response mediated by the hypoxia… Expand