Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Hypoxia-Inducible Factor Pathway

Known as: Hypoxia-Inducible Factor in the Cardiovascular System 
Hypoxia (or low O2 levels) affects various pathologies. First, tissue ischemia, a variation in O2 tension caused by hypoxia/reoxygenation, can lead… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
The hypoxia-inducible transcription factor (HIF) co-ordinates the response of tumours to low oxygen by stimulating genes involved… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Review
2012
Review
2012
Research into the mechanisms of human adaptation to the hypoxic environment of high altitude is of great interest to the fields… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
2012
2012
BACKGROUND Venous hypoxia has been postulated to contribute to varicose vein (VV) formation. Direct measurements of vein wall… Expand
Highly Cited
2011
Highly Cited
2011
Background: Segmental bone loss remains a challenging clinical problem.A frequent mitigating factor is inadequate blood supply… Expand
Highly Cited
2009
Highly Cited
2009
Muscle regeneration involves the coordination of myogenesis and revascularization to restore proper muscle function. Myogenesis… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2009
Highly Cited
2009
Hypoxia-inducible factor (HIF) plays an important role in cell survival by regulating iron, antioxidant defense, and… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Review
2008
Review
2008
The transcription factor complex hypoxia-inducible factor (HIF)-1 controls the expression of most genes involved in adaptation to… Expand
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Review
2008
Review
2008
Purpose of review To provide an overview of the recent advances in the understanding of the molecular mechanisms governing the… Expand
Review
2005
Review
2005
Much of the interest in angiogenesis and hypoxia has led to investigating diagnostic imaging methodologies and developing… Expand
Highly Cited
2004
Highly Cited
2004
Homeostasis under hypoxic conditions is maintained through a coordinated transcriptional response mediated by the hypoxia… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5