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Hypoxia Inducible Factor Family

Known as: HIF Factor, HIF, Hypoxia Inducible Factor 
A family of basic helix-loop-helix heterodimeric transcription factors that activate gene expression when oxygen levels decrease in the cellular… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Roxadustat (Ai Rui Zhuo® in China) is an orally administered, small molecule hypoxia-inducible factor (HIF) prolyl hydroxylase… Expand
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Review
2019
Review
2019
The field of hereditary kidney cancer has begun to mature following the identification of several germline syndromes that define… Expand
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Review
2019
Review
2019
Exosomes represent an important group of extracellular vesicles with a defined size between 40 and 150 nm and cup-shaped… Expand
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Review
2018
Review
2018
Hypoxia is a condition always present in tumor environment owing to the fast growth of tumor cells not supported by adequate… Expand
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Review
2018
Review
2018
Sorafenib, a multikinase inhibitor with antiproliferative, antiangiogenic, and proapoptotic properties, constitutes the only… Expand
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Review
2018
Review
2018
Hypoxia-inducible factors (HIFs), a family of transcription factors activated by hypoxia, consist of three α-subunits (HIF1… Expand
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Review
2017
Review
2017
Investigation into the regulation of the erythropoietin gene by oxygen led to the discovery of a process of direct oxygen sensing… Expand
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Review
2017
Review
2017
Hypoxia is a condition of insufficient tissue oxygenation, which is observed during normal development as well as tumorigenesis… Expand
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Review
2016
Review
2016
Hypoxia is an important micro-environmental characteristic of rheumatoid arthritis (RA). Hypoxia-inducible factors (HIF) are key… Expand
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Highly Cited
2001
Highly Cited
2001
Hypoxia-inducible factor (HIF) is a transcriptional complex that plays a central role in the regulation of gene expression by… Expand
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