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The last decade has witnessed a major reassessment of our perceptions about the acute coronary syndromes. Today, we recognize… Expand The plasma clearance of intestinally derived remnant lipoproteins by the liver is a process that likely involves three steps. Our… Expand Type III hyperlipoproteinemia (HLP) is a genetic disorder characterized by accumulation of remnant lipoproteins in the plasma and… Expand Apolipoprotein E is a plasma protein that serves as a ligand for low density lipoprotein receptors and, through its interaction… Expand The apo E locus contributes to determining the variation in plasma cholesterol levels of healthy and diseased populations. It… Expand The hypothesis that plasma chylomicrons in persons who ingest a cholesterol-rich diet are atherogenic is evaluated. Evidence is… Expand Abstract The survival experience of 39 patients receiving long-term regular hemodialysis in Seattle since 1960 was studied with… Expand Abstract Platelet function was studied in 17 patients with Type II hyperlipoproteinemia. As compared with 26 normal subjects… Expand Analysis of cardiovascular status in adult relatives of 116 kindred affected with familial hyperbetalipoproteinemia (type II… Expand Many studies of atherosclerosis have indicated hyperlipidaemia as a predisposing factor to vascular disease. The relationship… Expand