Hypercholesterolemia, Familial

Known as: Lipoproteinemia, Hyper-Low Density, Hyperlipoproteinemia Type II, Familial Hypercholesterolemic Xanthomatoses 
A group of familial disorders characterized by elevated circulating cholesterol contained in either LOW-DENSITY LIPOPROTEINS alone or also in VERY… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
OBJECTIVE The development of these guidelines is mandated by the American Association of Clinical Endocrinologists (AACE) Board… (More)
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Highly Cited
2011
Highly Cited
2011
The familial hypercholesterolemias (FH) are a group of genetic defects resulting in severe elevations of blood cholesterol levels… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Torcetrapib, an inhibitor of cholesteryl ester transfer protein, may reduce atherosclerotic vascular disease by… (More)
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Review
2007
Review
2007
Familial hypercholesterolemia (FH) is characterized by raised serum LDL cholesterol levels, which result in excess deposition of… (More)
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Review
2004
Review
2004
Familial hypercholesterolemia (FH) is a genetic disorder of lipoprotein metabolism characterized by very high plasma… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Neural apoptosis-regulated convertase (NARC)-1 is the newest member of the proprotein convertase family implicated in… (More)
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Highly Cited
1992
Highly Cited
1992
Endothelial dysfunction is an early event in experimental studies of atherogenesis, preceding formation of plaques. We have… (More)
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Highly Cited
1990
Highly Cited
1990
We conducted a randomized, controlled trial in 72 patients with heterozygous familial hypercholesterolemia to test whether… (More)
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Highly Cited
1976
Highly Cited
1976
Cultured fibroblasts derived from patients with homozygous familial hypercholesterolemia, which lack functional low density… (More)
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Highly Cited
1974
Highly Cited
1974
‘*51-Labeled low density lipoproteins were found to associate with monolayers of cultured normal fibroblasts by two processes… (More)
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