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Hutchinson's Melanotic Freckle

Known as: Malignant Lentigo, lentigo malignant, Hutchinson's Melanotic Freckle [Disease/Finding] 
An atypical proliferation of atypical melanocytes in the dermal-epidermal junction, without infiltration of the papillary or reticular dermis. The… 
National Institutes of Health

Related topics

Related topics

26 relations
Blood supply aspectsBody tissueDermal-epidermal junctionIn Blood

Broader (2)

Lentigomelanoma

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Characterization of the cellular infiltrate during successful topical treatment of lentigo maligna with imiquimod
Lentigo maligna (LM) is an in situ melanoma which usually occurs in sun‐damaged skin on the head and neck of elderly patients… 
Highly Cited
2001
Highly Cited
2001
Treatment of head and neck melanoma, lentigo maligna subtype: a practical surgical technique.
Melanoma with the lentigo maligna histological pattern often provides a significant and difficult challenge to the head and neck… 
Highly Cited
2000
Highly Cited
2000
Concurrent Ki-67 and p53 Immunolabeling in Cutaneous Melanocytic Neoplasms: An Adjunct for Recognition of the Vertical Growth Phase in Malignant Melanomas?
Ki-67 labeling of paraffin sections has been correlated with the number of cells in non-Go phases of the replicative cell cycle… 
Highly Cited
1998
Highly Cited
1998
p16INK4a expression is frequently decreased and associated with 9p21 loss of heterozygosity in sporadic melanoma
The product of the p16/INK4a/CDKN2/MTS1 tumor‐suppressor gene acts as a negative cell cycle regulator by inhibiting G1 cyclin… 
Highly Cited
1990
Highly Cited
1990
Immunohistochemical study of melanocytic nevus and malignant melanoma with monoclonal antibodies against s‐100 subunits
Immunohistochemical localization of S‐100 protein α and β subunits in the cells of melanocytic nevi and malignant melanomas was… 
Highly Cited
1985
Highly Cited
1985
Cutaneous malignant melanoma in association with other skin cancers.
A case-control study of 232 cases of cutaneous malignant melanoma and 232 matched controls was performed to assess the… 
Highly Cited
1976
Highly Cited
1976
On the nature of desmoplastic melanoma
Pathologic study demonstrated lentigo maligna melanoma in three of four cases of desmoplastic melanoma and demonstrated spindle… 
Review
1970
Review
1970
Hutchinson's melanotic freckle in oral mucous membrane
The occurrence of Hutchinson's melanotic freckle in the floor of the mouth is reported in a patient who had previously undergone… 
Highly Cited
1967
Highly Cited
1967
Loss of melanotic phenotype in vitro by differentiated retinal pigment cells: demonstration of mechanisms involved.
Highly Cited
1949
Highly Cited
1949
The osseous lesions of sarcoidosis.
In the fifty years which have passed since Caesar Boeck (1) first described an apparently rare dermatologic condition which he… 
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