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Human Combinatorial Antibody Library-based Monoclonal Antibody VAY736

Known as: HuCAL-based Antibody VAY736, VAY736 
A fully human combinatorial antibody library (HuCAL)-derived monoclonal antibody targeting the B-cell-activating factor receptor (BAFF-R), with… 
National Institutes of Health

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NCIt Antineoplastic Agent Terminologyantigen binding

Papers overview

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2019
2019
Faculty Opinions recommendation of Treatment of primary Sjögren's syndrome with ianalumab (VAY736) targeting B cells by BAFF receptor blockade coupled with enhanced, antibody-dependent cellular…
  • William St Clair
  • Faculty Opinions – Post-Publication Peer Review…
  • 2019
  • Corpus ID: 265870742
2018
2018
AB0632 Essdai domain evaluation of primary sjÖgren’s syndrome (PSS) patients enrolled in two independent poc studies indicates differential utility of domains for trial inclusion and composite…
Background According to international consensus, disease activity in primary Sjögren’s syndrome (pSS) patients shall be scored… 
2017
2017
SAT0301 Serum autoantibody profiling of primary sjÖgren's syndrome patients reveals novel biomarkers associated with the disease, disease activity, and clinical response to vay736
Background Overexpression of B cell activating factor (BAFF) in salivary glands contributes to the pathogenesis of primary Sj… 
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