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Human Combinatorial Antibody Library-based Monoclonal Antibody VAY736

Known as: HuCAL-based Antibody VAY736, VAY736 
A fully human combinatorial antibody library (HuCAL)-derived monoclonal antibody targeting the B-cell-activating factor receptor (BAFF-R), with… 
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
Objectives To evaluate the efficacy and safety of ianalumab (VAY736), a B cell-depleting, B cell activating factor receptor… 
2019
2019
Blocking BAFF-R early in ALL promotes killing of leukemic cells. However, if given at later disease stages, efficacy is limited… 
2018
2018
Background According to international consensus, disease activity in primary Sjögren’s syndrome (pSS) patients shall be scored… 
2017
2017
Background Overexpression of B cell activating factor (BAFF) contributes to the pathogenesis of primary Sjögren's syndrome (pSS… 
2017
2017
Background Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting wide range of systems including the… 
2017
2017
Background Overexpression of B cell activating factor (BAFF) in salivary glands contributes to the pathogenesis of primary Sj… 
2016
2016
Background VAY736 is a novel, defucosylated, human IgG1 mAb targeting the receptor for B cell activating Factor of the TNF family…