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Human Beta-1,4-Galactosyltransferase 6

Known as: Beta4Gal-T6, Glucosylceramide Beta-1,4-Galactosyltransferase, Lactosylceramide Synthase 
Beta-1,4-galactosyltransferase 6 (382 aa, ~45 kDa) is encoded by the human B4GALT6 gene. This protein plays a role in the glycosylation of ceramides.
National Institutes of Health

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8 relations
B4GALT6 geneCarbohydrate MetabolismEnzyme GeneGalactosyltransferases

Papers overview

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2007
2007
Trichothecenes induce accumulation of glucosylceramide in neural cells by interfering with lactosylceramide synthase activity.
2004
2004
GD3 expression by cultured human tumor cells of neuroectodermal origin
SummarySeven monoclonal antibodies (mAbs) reactive with ganglioside II3(NeuAc)2-LacCer (GD3) were generated; four of these mAbs… 
1994
1994
A truncated epoxy-glucosylceramide uncouples glycosphingolipid biosynthesis by decreasing lactosylceramide synthase activity.
1994
1994
Endocytosis and recycling of gangliosides in a human melanoma cell line: inhibitory effect of brefeldin A and monensin.
The internalization and recycling of glycosphingolipids (GLs), added exogenously to cells, has been shown in a number of systems… 
1993
1993
Different binding capacities of influenza A and Sendai viruses to gangliosides from human granulocytes
The structures of gangliosides from human granulocytes were elucidated by fast atom bombardment mass spectrometry and by gas… 
1993
1993
Luteal phase-characteristic induction of I3SO3-GalCer in human cervical epithelia and uterine endometria, and follicular phase-characteristic formation of a ganglioside-derived negative charge…
1990
1990
Accumulation of highly acidic sulfated glycosphingolipids in human hepatocellular carcinoma defined by a series of monoclonal antibodies.
An accumulation of sulfated and very complex, highly acidic glycolipids was observed in cultured human hepatocellular carcinoma… 
1988
1988
Monoclonal antibodies directed to a disulfated glycosphingolipid, SB1a (GgOse4Cer-II3IV3-bis-sulfate), associated with human hepatocellular carcinoma.
Two murine monoclonal antibodies, 2H6G5 (IgM) and 4A9E10 (IgG3), were obtained by using either cultured human hepatocellular… 
1988
1988
Melanoma-associated gangliosides in the fish genus Xiphophorus.
Gangliosides from benign and malignant melanomas and from normal skin of the fish genus Xiphophorus were isolated and analyzed by… 
1983
1983
Gangliosides of human chronic lymphocytic leukemia and hairy cells.
Gangliosides were purified from the cells of two patients with hairy cell leukemia and one patient with chronic lymphocytic… 
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