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Human Adenovirus Type 5 Early Region 1
Known as:
Ad5E1
A region of the adenovirus type 5 genome that contains the transforming early genes E1A and E1B.
National Institutes of Health
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Related topics
Related topics
2 relations
Adenoviruses
Virus Physiological Phenomena
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
CD4+ T‐cell‐dependent tumour rejection in an immune‐privileged environment requires macrophages
D. Dace
,
Peter W. Chen
,
J. Niederkorn
Immunology
2008
Corpus ID: 41178910
Although intraocular tumours reside in an immune‐privileged site, they can circumvent immune privilege and undergo rejection…
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2003
2003
Protection Against Experimental Autoimmune Encephalomyelitis Generated by a Recombinant Adenovirus Vector Expressing the Vβ8.2 TCR Is Disrupted by Coadministration with Vectors Expressing Either IL-4…
T. Braciak
,
B. Pedersen
,
+8 authors
Vipin Kumar
The Journal of Immunology
2003
Corpus ID: 31120858
Adenovirus vectors are increasingly being used for genetic vaccination and may prove highly suitable for intervention in…
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Highly Cited
2003
Highly Cited
2003
Role of TRAIL and IFN-γ in CD4+ T Cell-Dependent Tumor Rejection in the Anterior Chamber of the Eye 1
Shixuan Wang
,
Z. Boonman
,
+4 authors
J. Niederkorn
The Journal of Immunology
2003
Corpus ID: 44338088
Although the anterior chamber of the eye expresses immune privilege, some ocular tumors succumb to immune rejection. Previous…
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Highly Cited
1999
Highly Cited
1999
Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial
A. Stewart
,
N. Lassam
,
+11 authors
F. Graham
Gene Therapy
1999
Corpus ID: 36942984
We conducted a phase 1 trial of direct injection of an E1,E3-deleted adenovirus encoding interleukin-2 (AdCAIL-2) into…
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Highly Cited
1998
Highly Cited
1998
Enhancement of tumor outgrowth through CTL tolerization after peptide vaccination is avoided by peptide presentation on dendritic cells.
R. Toes
,
E. V. D. van der Voort
,
+6 authors
C. Melief
Journal of immunology
1998
Corpus ID: 21451755
Synthetic peptide-based vaccines have been shown to induce potent protective and therapeutic T cell-mediated immunity in…
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Highly Cited
1998
Highly Cited
1998
A double recombinant adenovirus expressing the costimulatory molecule B7-1 (murine) and human IL-2 induces complete tumor regression in a murine breast adenocarcinoma model.
P. Emtage
,
Y. Wan
,
J. Bramson
,
F. Graham
,
J. Gauldie
Journal of immunology
1998
Corpus ID: 13080528
Tumors that express tumor-specific antigens can maintain growth in an immunocompetent organism. Current hypotheses tend toward T…
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Highly Cited
1996
Highly Cited
1996
Enhanced tumor outgrowth after peptide vaccination. Functional deletion of tumor-specific CTL induced by peptide vaccination can lead to the inability to reject tumors.
R. Toes
,
R. J. Blom
,
R. Offringa
,
W. Kast
,
C. Melief
Journal of immunology
1996
Corpus ID: 234853
CTL can play an important role in the defense against tumors. Protective CTL-mediated immunity can be established in animal tumor…
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Highly Cited
1996
Highly Cited
1996
Protective antitumor immunity induced by immunization with completely allogeneic tumor cells.
R. Toes
,
R. J. Blom
,
E. V. D. van der Voort
,
R. Offringa
,
C. Melief
,
W. Kast
Cancer research
1996
Corpus ID: 7429137
We have shown previously that immunization of B6 mice (H-2b) with tumor cells of B6 origin transformed by the human adenovirus…
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Highly Cited
1995
Highly Cited
1995
An adenovirus type 5 early region 1B-encoded CTL epitope-mediating tumor eradication by CTL clones is down-modulated by an activated ras oncogene.
R. Toes
,
R. Offringa
,
+4 authors
W. Kast
Journal of immunology
1995
Corpus ID: 20027039
Mouse embryo cells (C57BL/6, H-2b) transformed by the E1A and E1B genes of adenovirus type 5 (Ad5E1 MEC) are highly immunogenic…
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Highly Cited
1986
Highly Cited
1986
Adenovirus E1A‐mediated regulation of class I MHC expression.
R. Vaessen
,
A. Houweling
,
A. Israel
,
P. Kourilsky
,
A. Eb
The EMBO journal
1986
Corpus ID: 44263792
Expression of class I MHC transplantation antigens has been shown to be reduced in baby rat kidney (BRK) cells transformed by…
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