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Human Adenovirus Type 5 Early Region 1

Known as: Ad5E1 
A region of the adenovirus type 5 genome that contains the transforming early genes E1A and E1B.
National Institutes of Health

Papers overview

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2008
2008
Although intraocular tumours reside in an immune‐privileged site, they can circumvent immune privilege and undergo rejection… Expand
Highly Cited
2003
Highly Cited
2003
Although the anterior chamber of the eye expresses immune privilege, some ocular tumors succumb to immune rejection. Previous… Expand
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2003
2003
Adenovirus vectors are increasingly being used for genetic vaccination and may prove highly suitable for intervention in… Expand
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Highly Cited
1999
Highly Cited
1999
We conducted a phase 1 trial of direct injection of an E1,E3-deleted adenovirus encoding interleukin-2 (AdCAIL-2) into… Expand
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Highly Cited
1998
Highly Cited
1998
Synthetic peptide-based vaccines have been shown to induce potent protective and therapeutic T cell-mediated immunity in… Expand
Highly Cited
1998
Highly Cited
1998
Tumors that express tumor-specific antigens can maintain growth in an immunocompetent organism. Current hypotheses tend toward T… Expand
Highly Cited
1996
Highly Cited
1996
CTL can play an important role in the defense against tumors. Protective CTL-mediated immunity can be established in animal tumor… Expand
Highly Cited
1996
Highly Cited
1996
We have shown previously that immunization of B6 mice (H-2b) with tumor cells of B6 origin transformed by the human adenovirus… Expand
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Highly Cited
1995
Highly Cited
1995
Mouse embryo cells (C57BL/6, H-2b) transformed by the E1A and E1B genes of adenovirus type 5 (Ad5E1 MEC) are highly immunogenic… Expand
1986
1986
Expression of class I MHC transplantation antigens has been shown to be reduced in baby rat kidney (BRK) cells transformed by… Expand