Human Adenovirus Type 5 Early Region 1

Although intraocular tumours reside in an immune‐privileged site, they can circumvent immune privilege and undergo rejection… Expand

Although the anterior chamber of the eye expresses immune privilege, some ocular tumors succumb to immune rejection. Previous… Expand

Adenovirus vectors are increasingly being used for genetic vaccination and may prove highly suitable for intervention in… Expand

We conducted a phase 1 trial of direct injection of an E1,E3-deleted adenovirus encoding interleukin-2 (AdCAIL-2) into… Expand

Synthetic peptide-based vaccines have been shown to induce potent protective and therapeutic T cell-mediated immunity in… Expand

Tumors that express tumor-specific antigens can maintain growth in an immunocompetent organism. Current hypotheses tend toward T… Expand

CTL can play an important role in the defense against tumors. Protective CTL-mediated immunity can be established in animal tumor… Expand

We have shown previously that immunization of B6 mice (H-2b) with tumor cells of B6 origin transformed by the human adenovirus… Expand

Mouse embryo cells (C57BL/6, H-2b) transformed by the E1A and E1B genes of adenovirus type 5 (Ad5E1 MEC) are highly immunogenic… Expand

Expression of class I MHC transplantation antigens has been shown to be reduced in baby rat kidney (BRK) cells transformed by… Expand