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Human Adenovirus Type 5 Early Region 1

Known as: Ad5E1 
A region of the adenovirus type 5 genome that contains the transforming early genes E1A and E1B.
National Institutes of Health

Papers overview

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2008
2008
Although intraocular tumours reside in an immune-privileged site, they can circumvent immune privilege and undergo rejection… Expand
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2007
2007
Although intraocular tumors reside in an immune-privileged environment, T cells can circumvent immune privilege and mediate tumor… Expand
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2003
2003
Although the anterior chamber of the eye expresses immune privilege, some ocular tumors succumb to immune rejection. Previous… Expand
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Highly Cited
1999
Highly Cited
1999
We conducted a phase 1 trial of direct injection of an E1,E3-deleted adenovirus encoding interleukin-2 (AdCAIL-2) into… Expand
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1998
1998
Tumors that express tumor-specific antigens can maintain growth in an immunocompetent organism. Current hypotheses tend toward T… Expand
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Highly Cited
1998
Highly Cited
1998
Synthetic peptide-based vaccines have been shown to induce potent protective and therapeutic T cell-mediated immunity in… Expand
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Highly Cited
1996
Highly Cited
1996
CTL can play an important role in the defense against tumors. Protective CTL-mediated immunity can be established in animal tumor… Expand
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1996
1996
We have shown previously that immunization of B6 mice (H-2b) with tumor cells of B6 origin transformed by the human adenovirus… Expand
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1996
1996
Adenovirus E1A proteins modulate the expression of a large variety of genes in transformed cells by either stimulating or… Expand
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1995
1995
Mouse embryo cells (C57BL/6, H-2b) transformed by the E1A and E1B genes of adenovirus type 5 (Ad5E1 MEC) are highly immunogenic… Expand
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