Homogentisate 1,2-dioxygenase

Known as: Homogentisate 1,2 Dioxygenase, Oxidase, Homogentisic Acid, Homogentisate Dioxygenase 
A mononuclear Fe(II)-dependent oxygenase, this enzyme catalyzes the conversion of homogentisate to 4-maleylacetoacetate, the third step in the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2018
0102019572017

Papers overview

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2015
2015
Alkaptonuria is an ultra-rare autosomal recessive disease developed from the lack of homogentisate 1,2-dioxygenase (HGD) activity… (More)
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2007
2007
Tocopherols are lipophilic antioxidants that are synthesized exclusively in photosynthetic organisms. In most higher plants… (More)
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2004
2004
Homogentisate 1,2-dioxygenase (HGD) is a mononuclear Fe(II)-dependent oxygenase that catalyzes the third step in the pathway for… (More)
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Highly Cited
2004
Highly Cited
2004
Pseudomonas putida metabolizes Phe and Tyr through a peripheral pathway involving hydroxylation of Phe to Tyr (PhhAB), conversion… (More)
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Highly Cited
2003
Highly Cited
2003
Tocopherols are amphipathic antioxidants synthesized exclusively by photosynthetic organisms. Tocopherol levels change… (More)
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Highly Cited
2002
Highly Cited
2002
Tocopherols, synthesized by photosynthetic organisms, are micronutrients with antioxidant properties that play important roles in… (More)
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2000
2000
Homogentisate dioxygenase (HGO) cleaves the aromatic ring during the metabolic degradation of Phe and Tyr. HGO deficiency causes… (More)
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1998
1998
Alkaptonuria (AKU) is caused by lack of homogentisate 1, 2 dioxygenase (HGO) activity. From the complete sequence of a human HGO… (More)
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1997
1997
Alkaptonuria (AKU; McKusick No. 203500), a rare hereditary disorder of the phenylalanine catabolism, was the first disease to be… (More)
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Highly Cited
1975
Highly Cited
1975
The enzyme 4-hydroxyphenylacetate, NAD(P)H:oxygen oxidoreductase (1-hydroxylating) (EC 1.14.13 ...; 4-hydroxyphenylacetate 1… (More)
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