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Homogentisate 1,2-dioxygenase

Known as: Homogentisate 1,2 Dioxygenase, Oxidase, Homogentisic Acid, Homogentisate Dioxygenase 
A mononuclear Fe(II)-dependent oxygenase, this enzyme catalyzes the conversion of homogentisate to 4-maleylacetoacetate, the third step in the… Expand
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
Tocopherols and tocotrienols, collectively known as tocochromanols, are the major lipid-soluble antioxidants in maize (Zea mays L… Expand
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2011
2011
The biosynthesis of the tocotrienol and tocopherol forms of vitamin E is initiated by prenylation of homogentisate… Expand
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Highly Cited
2004
Highly Cited
2004
Pseudomonas putida metabolizes Phe and Tyr through a peripheral pathway involving hydroxylation of Phe to Tyr (PhhAB), conversion… Expand
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Highly Cited
2003
Highly Cited
2003
Tocopherols are amphipathic antioxidants synthesized exclusively by photosynthetic organisms. Tocopherol levels change… Expand
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Highly Cited
2002
Highly Cited
2002
Tocopherols, synthesized by photosynthetic organisms, are micronutrients with antioxidant properties that play important roles in… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Alkaptonuria, caused by mutations in the HGO gene and a deficiency of homogentisate 1,2-dioxygenase, results in an… Expand
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Highly Cited
2000
Highly Cited
2000
Homogentisate dioxygenase (HGO) cleaves the aromatic ring during the metabolic degradation of Phe and Tyr. HGO deficiency causes… Expand
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1997
1997
Alkaptonuria (AKU; McKusick No. 203500), a rare hereditary disorder of the phenylalanine catabolism, was the first disease to be… Expand
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1994
1994
Alkaptonuria is a human hereditary metabolic disease characterized by a very high urinary excretion of homogentisic acid, an… Expand
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Highly Cited
1975
Highly Cited
1975
The enzyme 4-hydroxyphenylacetate, NAD(P)H:oxygen oxidoreductase (1-hydroxylating) (EC 1.14.13 ...; 4-hydroxyphenylacetate 1… Expand
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