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Homidium Chloride

Known as: 3,8-Diamino-5-ethyl-6-phenylphenanthridinium Chloride, 2,7-diamino-9-phenyl-10-ethylphenanthridinium Chloride, Novidium Chloride 
The chloride salt of ethidium (a fluorochrome), Ethidium Chloride intercalates within double-stranded nucleic acids, particularly DNA. In molecular… Expand
National Institutes of Health

Papers overview

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2012
2012
Abstract Background: Chemotherapy which is one of the major methods for controlling trypanosomal infections is beset with several… Expand
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2010
2010
Anaemia and immunosuppresion have been shown to be a cardinal feature in African trypanosomosis. In this study, we have evaluated… Expand
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2005
2005
Resistance to trypanocidal drugs has been detected in various African countries and is a serious impediment to the control of… Expand
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Highly Cited
1997
Highly Cited
1997
Ten trypanosome isolates were collected at random from cattle at Ghibe, Ethiopia, in February 1993 and all shown to be savannah… Expand
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1995
1995
  • S. Pedersen
  • Molecular pharmacology
  • 1995
  • Corpus ID: 7816803
Three azido derivatives of ethidium bromide, a potent noncompetitive antagonist of the nicotinic acetylcholine receptor from… Expand
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Highly Cited
1993
Highly Cited
1993
In July 1989, blood samples were collected from parasitaemic cattle in the Ghibe valley, Ethiopia, frozen in liquid nitrogen and… Expand
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Highly Cited
1984
Highly Cited
1984
Antisera raised against Trypanosoma evansi and T. congolense were used in a double antibody sandwich enzyme immunosorbent assay… Expand
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1978
1978
A bis-phenanthridinium salt has been synthesized and its DNA-binding studied. Evidence provided by UV and CD spectra, by thermal… Expand
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Highly Cited
1971
Highly Cited
1971
Abstract Ten closed SV40 DNA's with superhelix densities (superhelical turns per ten base pairs) ranging from −0.007 to −0.085… Expand
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Highly Cited
1971
Highly Cited
1971
Two strains of T. congolense and two strains of T. vivax, resistant to normal therapeutic doses of trypanocidal drugs, were… Expand
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