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Homeobox Protein SIX2

Known as: Sine Oculis Homeobox (Drosophila) Homolog 2, Sine Oculis Homeobox Homolog 2, Sine Oculis Homeobox Homolog 2 (Drosophila) 
Homeobox protein SIX2 (291 aa, ~32 kDa) is encoded by the human SIX2 gene. This protein is involved in the regulation of transcription.
National Institutes of Health

Related topics

Related topics

7 relations
DNA-Binding ProteinsGenes, RegulatorHomeodomain ProteinsSIX2 gene
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Papers overview

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Highly Cited
2011
Highly Cited
2011
Automated protein-DNA interaction screening of Drosophila regulatory elements
Drosophila melanogaster has one of the best characterized metazoan genomes in terms of functionally annotated regulatory elements… Expand
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2010
2010
Crystal structure of ED‐Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor
Eya proteins are transcription factors that play pivotal roles in organ formation during development by mediating interactions… Expand
2010
2010
Enforcing biphasic eye development in a directly developing insect by transient knockdown of single eye selector genes.
The visual system of indirectly developing insects such as Drosophila passes through two phases of development. Larval eyes form… Expand
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2009
2009
Retinal determination genes as targets and possible effectors of extracellular signals.
Retinal determination genes are sufficient to specify eyes in ectopic locations, raising the question of how these master… Expand
2008
2008
Cell-type-specific transcription of prospero is controlled by combinatorial signaling in the Drosophila eye
In Drosophila, Notch and Egfr signaling regulate the determination of many cell types, and yet how these common signals generate… Expand
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2007
2007
distal antenna and distal antenna-related function in the retinal determination network during eye development in Drosophila.
Drosophila eye specification occurs through the activity of the retinal determination (RD) network, which includes the Eyeless… Expand
Highly Cited
2006
Highly Cited
2006
Genome-wide identification of direct targets of the Drosophila retinal determination protein Eyeless.
The discovery of direct downstream targets of transcription factors (TFs) is necessary for understanding the genetic mechanisms… Expand
2005
2005
Pointed regulates an eye-specific transcriptional enhancer in the Drosophila hedgehog gene, which is required for the movement of the morphogenetic furrow
Drosophila development depends on stable boundaries between cellular territories, such as the embryonic parasegment boundaries… Expand
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2000
2000
The determination of histamine in the Drosophila head
Histamine is a neurotransmitter at arthropod photoreceptors. Even though the fruit fly, Drosophila melanogaster, is a widely used… Expand
1984
1984
Absence of diglyceride kinase activity in the photoreceptor cells of Drosophila mutants.
Diglyceride kinase (DG) activity was found to be almost absent in the photoreceptor cells of Drosophila vision mutants, norpA (no… Expand
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