FAQ

Holo-[acyl-carrier-protein] synthase

Known as: 4'-phosphopantetheine-apofatty acid synthetase transferase, phosphopantetheine-protein transferase, holo-(acyl-carrier-protein) synthase 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2011
012319952011

Related topics

Related topics

3 relations
AASDHPPT geneholo-[acyl-carrier protein] synthase activity

Broader (1)

Transferases (Other Substituted Phosphate Groups)

Related mentions per year

Related mentions per year

1972-2018
197019801990200020102020
Holo-[acyl-carrier-protein] synthase
holo-[acyl-carrier protein] synthase activity
AASDHPPT gene
Transferases (Other Substituted Phosphate Groups)

Papers overview

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2008
2008
An ACP structural switch: conformational differences between the apo and holo forms of the actinorhodin polyketide synthase acyl carrier protein.
The actinorhodin (act) synthase acyl carrier protein (ACP) from Streptomyces coelicolor plays a central role in polyketide… (More)
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2006
2006
The phosphopantetheinyl transferase superfamily: phylogenetic analysis and functional implications in cyanobacteria.
Phosphopantetheinyl transferases (PPTs) are a superfamily of essential enzymes required for the synthesis of a wide range of… (More)
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2005
2005
Use of structure-based drug design approaches to obtain novel anthranilic acid acyl carrier protein synthase inhibitors.
Acyl carrier protein synthase (AcpS) catalyzes the transfer of the 4'-phosphopantetheinyl group from the coenzyme A to a serine… (More)
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2004
2004
Anthranilate 4H-oxazol-5-ones: novel small molecule antibacterial acyl carrier protein synthase (AcpS) inhibitors.
D-optimal design and Projection to Latent Structures (PLS) analysis were used to optimize screening hit 5 (B. subtilis AcpS IC(50… (More)
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2004
2004
Structure-based mutational analysis of the 4'-phosphopantetheinyl transferases Sfp from Bacillus subtilis: carrier protein recognition and reaction mechanism.
The activation of apo-peptidyl carrier proteins (PCPs) of nonribosomal peptide synthetases (NRPSs), apo-acyl carrier proteins… (More)
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2001
2001
Solution structure of B. subtilis acyl carrier protein.
BACKGROUND Acyl carrier protein (ACP) is a fundamental component of fatty acid biosynthesis in which the fatty acid chain is… (More)
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2000
2000
Biochemical and molecular analyses of the Streptococcus pneumoniae acyl carrier protein synthase, an enzyme essential for fatty acid biosynthesis.
Acyl carrier protein synthase (AcpS) is an essential enzyme in the biosynthesis of fatty acids in all bacteria. AcpS catalyzes… (More)
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2000
2000
Crystal structure of Streptococcus pneumoniae acyl carrier protein synthase: an essential enzyme in bacterial fatty acid biosynthesis.
Acyl carrier protein synthase (AcpS) catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty… (More)
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1997
1997
Post-translational modification of heterologously expressed Streptomyces type II polyketide synthase acyl carrier proteins.
Expression in Escherichia coli of Streptomyces acyl carrier proteins (ACPs) associated with polyketide biosynthesis using the pT7… (More)
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1995
1995
Cloning, overproduction, and characterization of the Escherichia coli holo-acyl carrier protein synthase.
Holo-acyl carrier protein synthase (ACPS) transfers the 4'-phosphopantetheine (4'-PP) moiety from coenzyme A (CoA) to Ser-36 of… (More)
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