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Holo-[acyl-carrier-protein] synthase

Known as: 4'-phosphopantetheine-apofatty acid synthetase transferase, phosphopantetheine-protein transferase, holo-(acyl-carrier-protein) synthase 
 
National Institutes of Health

Related topics

Related topics

3 relations
AASDHPPT geneholo-[acyl-carrier protein] synthase activity

Broader (1)

Transferases (Other Substituted Phosphate Groups)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein
The actinorhodin (act) synthase acyl carrier protein (ACP) from Streptomyces coelicolor plays a central role in polyketide… Expand
Highly Cited
2006
Highly Cited
2006
The Phosphopantetheinyl Transferase Superfamily: Phylogenetic Analysis and Functional Implications in Cyanobacteria
ABSTRACT Phosphopantetheinyl transferases (PPTs) are a superfamily of essential enzymes required for the synthesis of a wide… Expand
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2005
2005
Self-malonylation is an intrinsic property of a chemically synthesized type II polyketide synthase acyl carrier protein.
During polyketide biosynthesis, malonyl groups are transferred to the acyl carrier protein (ACP) component of the polyketide… Expand
2005
2005
Use of structure-based drug design approaches to obtain novel anthranilic acid acyl carrier protein synthase inhibitors.
Acyl carrier protein synthase (AcpS) catalyzes the transfer of the 4'-phosphopantetheinyl group from the coenzyme A to a serine… Expand
Highly Cited
2004
Highly Cited
2004
Structure-based mutational analysis of the 4'-phosphopantetheinyl transferases Sfp from Bacillus subtilis: carrier protein recognition and reaction mechanism.
The activation of apo-peptidyl carrier proteins (PCPs) of nonribosomal peptide synthetases (NRPSs), apo-acyl carrier proteins… Expand
Highly Cited
2001
Highly Cited
2001
Solution structure of B. subtilis acyl carrier protein.
BACKGROUND Acyl carrier protein (ACP) is a fundamental component of fatty acid biosynthesis in which the fatty acid chain is… Expand
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Highly Cited
2000
Highly Cited
2000
Crystal structure of Streptococcus pneumoniae acyl carrier protein synthase: an essential enzyme in bacterial fatty acid biosynthesis
Acyl carrier protein synthase (AcpS) catalyzes the formation of holo‐ACP, which mediates the essential transfer of acyl fatty… Expand
2000
2000
Biochemical and Molecular Analyses of the Streptococcus pneumoniae Acyl Carrier Protein Synthase, an Enzyme Essential for Fatty Acid Biosynthesis*
Acyl carrier protein synthase (AcpS) is an essential enzyme in the biosynthesis of fatty acids in all bacteria. AcpS catalyzes… Expand
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1997
1997
Post‐translational modification of heterologously expressed Streptomyces type II polyketide synthase acyl carrier proteins
Expression in Escherichia coli of Streptomyces acyl carrier proteins (ACPs) associated with polyketide biosynthesis using the pT7… Expand
Highly Cited
1995
Highly Cited
1995
Cloning, Overproduction, and Characterization of the Escherichia coli Holo-acyl Carrier Protein Synthase (*)
Holo-acyl carrier protein synthase (ACPS) transfers the 4′-phosphopantetheine (4′-PP) moiety from coenzyme A (CoA) to Ser-36 of… Expand
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