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Holo-[acyl-carrier-protein] synthase
Known as:
4'-phosphopantetheine-apofatty acid synthetase transferase
, phosphopantetheine-protein transferase
, holo-(acyl-carrier-protein) synthase
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National Institutes of Health
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Related topics
Related topics
3 relations
AASDHPPT gene
holo-[acyl-carrier protein] synthase activity
Broader (1)
Transferases (Other Substituted Phosphate Groups)
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
An ACP Structural Switch: Conformational Differences between the Apo and Holo Forms of the Actinorhodin Polyketide Synthase Acyl Carrier Protein
Simon E Evans
,
Christopher Williams
,
+4 authors
M. Crump
Chembiochem : a European journal of chemical…
2008
Corpus ID: 24339456
The actinorhodin (act) synthase acyl carrier protein (ACP) from Streptomyces coelicolor plays a central role in polyketide…
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Highly Cited
2006
Highly Cited
2006
The Phosphopantetheinyl Transferase Superfamily: Phylogenetic Analysis and Functional Implications in Cyanobacteria
J. Copp
,
B. Neilan
Applied and Environmental Microbiology
2006
Corpus ID: 39999472
ABSTRACT Phosphopantetheinyl transferases (PPTs) are a superfamily of essential enzymes required for the synthesis of a wide…
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2005
2005
Self-malonylation is an intrinsic property of a chemically synthesized type II polyketide synthase acyl carrier protein.
C. Arthur
,
A. Szafranska
,
+7 authors
M. Crump
Biochemistry
2005
Corpus ID: 43554360
During polyketide biosynthesis, malonyl groups are transferred to the acyl carrier protein (ACP) component of the polyketide…
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2005
2005
Use of structure-based drug design approaches to obtain novel anthranilic acid acyl carrier protein synthase inhibitors.
D. Joseph-McCarthy
,
K. Parris
,
+16 authors
A. Gilbert
Journal of medicinal chemistry
2005
Corpus ID: 23617285
Acyl carrier protein synthase (AcpS) catalyzes the transfer of the 4'-phosphopantetheinyl group from the coenzyme A to a serine…
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Highly Cited
2004
Highly Cited
2004
Structure-based mutational analysis of the 4'-phosphopantetheinyl transferases Sfp from Bacillus subtilis: carrier protein recognition and reaction mechanism.
M. Mofid
,
Robert Finking
,
L. Essen
,
M. Marahiel
Biochemistry
2004
Corpus ID: 24852541
The activation of apo-peptidyl carrier proteins (PCPs) of nonribosomal peptide synthetases (NRPSs), apo-acyl carrier proteins…
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Highly Cited
2001
Highly Cited
2001
Solution structure of B. subtilis acyl carrier protein.
G. Y. Xu
,
A. Tam
,
L. Lin
,
J. Hixon
,
C. Fritz
,
R. Powers
Structure
2001
Corpus ID: 7544782
Highly Cited
2000
Highly Cited
2000
Crystal structure of Streptococcus pneumoniae acyl carrier protein synthase: an essential enzyme in bacterial fatty acid biosynthesis
N. Chirgadze
,
S. Briggs
,
K. A. McAllister
,
A. Fischl
,
G. Zhao
The EMBO journal
2000
Corpus ID: 22188348
Acyl carrier protein synthase (AcpS) catalyzes the formation of holo‐ACP, which mediates the essential transfer of acyl fatty…
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2000
2000
Biochemical and Molecular Analyses of the Streptococcus pneumoniae Acyl Carrier Protein Synthase, an Enzyme Essential for Fatty Acid Biosynthesis*
K. A. McAllister
,
R. Peery
,
T. Meier
,
A. Fischl
,
G. Zhao
The Journal of Biological Chemistry
2000
Corpus ID: 28324939
Acyl carrier protein synthase (AcpS) is an essential enzyme in the biosynthesis of fatty acids in all bacteria. AcpS catalyzes…
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1997
1997
Post‐translational modification of heterologously expressed Streptomyces type II polyketide synthase acyl carrier proteins
R. Cox
,
T. Hitchman
,
+4 authors
T. J. Simpson
FEBS letters
1997
Corpus ID: 10959786
Highly Cited
1995
Highly Cited
1995
Cloning, Overproduction, and Characterization of the Escherichia coli Holo-acyl Carrier Protein Synthase (*)
R. H. Lambalot
,
C. Walsh
The Journal of Biological Chemistry
1995
Corpus ID: 8738652
Holo-acyl carrier protein synthase (ACPS) transfers the 4′-phosphopantetheine (4′-PP) moiety from coenzyme A (CoA) to Ser-36 of…
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