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Histone Deacetylase Complexes

Known as: histone deacetylase complex, histone deacetylase complex location, Complexes, Histone Deacetylase 
A protein complex that possesses histone deacetylase activity. [GOC:mah]
National Institutes of Health

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Broader (1)

Histone Deacetylase

Papers overview

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Highly Cited
2006
Highly Cited
2006
ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression
Dynamic regulation of diverse nuclear processes is intimately linked to covalent modifications of chromatin. Much attention has… 
Highly Cited
2004
Highly Cited
2004
The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes
Regulation of gene expression by mitogen-activated protein kinases (MAPKs) is essential for proper cell adaptation to… 
Highly Cited
2001
Highly Cited
2001
CoREST is an integral component of the CoREST- human histone deacetylase complex.
Here we describe the components of a histone deacetylase (HDAC) complex that we term the CoREST-HDAC complex. CoREST-HDAC is… 
Highly Cited
1999
Highly Cited
1999
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.
ATP-dependent nucleosome remodeling and core histone acetylation and deacetylation represent mechanisms to alter nucleosome… 
Highly Cited
1999
Highly Cited
1999
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
Mammalian DNA is methylated at many CpG dinucleotides. The biological consequences of methylation are mediated by a family of… 
Highly Cited
1999
Highly Cited
1999
The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth
E7 is the main transforming protein of human papilloma virus type 16 (HPV16) which is implicated in the formation of cervical… 
Highly Cited
1999
Highly Cited
1999
BRCA1 interacts with components of the histone deacetylase complex.
  • R. YardenL. Brody
  • Proceedings of the National Academy of Sciences…
  • 1999
  • Corpus ID: 10062759
Germ-line mutations in the BRCA1 tumor-suppressor gene are associated with an increased susceptibility to breast and ovarian… 
Highly Cited
1998
Highly Cited
1998
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
Cytosine residues in the sequence 5′CpG (cytosine–guanine) are often postsynthetically methylated in animal genomes. CpG… 
Highly Cited
1998
Highly Cited
1998
Aberrant Recruitment of the Nuclear Receptor Corepressor-Histone Deacetylase Complex by the Acute Myeloid Leukemia Fusion Partner ETO
ABSTRACT Nuclear receptor corepressor (CoR)-histone deacetylase (HDAC) complex recruitment is indispensable for the biological… 
Highly Cited
1996
Highly Cited
1996
HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription.
Increased histone acetylation has been correlated with increased transcription, and regions of heterochromatin are generally… 
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