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Histone Deacetylase Complexes
Known as:
histone deacetylase complex
, histone deacetylase complex location
, Complexes, Histone Deacetylase
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A protein complex that possesses histone deacetylase activity. [GOC:mah]
National Institutes of Health
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Histone Deacetylase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression
Xiaobing Shi
,
T. Hong
,
+18 authors
O. Gozani
Nature
2006
Corpus ID: 1249972
Dynamic regulation of diverse nuclear processes is intimately linked to covalent modifications of chromatin. Much attention has…
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Highly Cited
2004
Highly Cited
2004
The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes
E. Nadal
,
Meritxell Zapater
,
P. Alepuz
,
L. Sumoy
,
Glòria Mas
,
F. Posas
Nature
2004
Corpus ID: 4392490
Regulation of gene expression by mitogen-activated protein kinases (MAPKs) is essential for proper cell adaptation to…
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Highly Cited
2001
Highly Cited
2001
CoREST is an integral component of the CoREST- human histone deacetylase complex.
A. You
,
J. Tong
,
C. Grozinger
,
S. Schreiber
Proceedings of the National Academy of Sciences…
2001
Corpus ID: 29712692
Here we describe the components of a histone deacetylase (HDAC) complex that we term the CoREST-HDAC complex. CoREST-HDAC is…
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Highly Cited
1999
Highly Cited
1999
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.
Y. Zhang
,
H. Ng
,
H. Erdjument-Bromage
,
P. Tempst
,
A. Bird
,
D. Reinberg
Genes & Development
1999
Corpus ID: 8395347
ATP-dependent nucleosome remodeling and core histone acetylation and deacetylation represent mechanisms to alter nucleosome…
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Highly Cited
1999
Highly Cited
1999
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
H. Ng
,
Yi Zhang
,
+6 authors
A. Bird
Nature Genetics
1999
Corpus ID: 6147725
Mammalian DNA is methylated at many CpG dinucleotides. The biological consequences of methylation are mediated by a family of…
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Highly Cited
1999
Highly Cited
1999
The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth
A. Brehm
,
S. Nielsen
,
+4 authors
T. Kouzarides
EMBO Journal
1999
Corpus ID: 13607715
E7 is the main transforming protein of human papilloma virus type 16 (HPV16) which is implicated in the formation of cervical…
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Highly Cited
1999
Highly Cited
1999
BRCA1 interacts with components of the histone deacetylase complex.
R. Yarden
,
L. Brody
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 10062759
Germ-line mutations in the BRCA1 tumor-suppressor gene are associated with an increased susceptibility to breast and ovarian…
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Highly Cited
1998
Highly Cited
1998
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
X. Nan
,
H. Ng
,
+4 authors
A. Bird
Nature
1998
Corpus ID: 4427745
Cytosine residues in the sequence 5′CpG (cytosine–guanine) are often postsynthetically methylated in animal genomes. CpG…
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Highly Cited
1998
Highly Cited
1998
Aberrant Recruitment of the Nuclear Receptor Corepressor-Histone Deacetylase Complex by the Acute Myeloid Leukemia Fusion Partner ETO
V. Gelmetti
,
Jinsong Zhang
,
M. Fanelli
,
S. Minucci
,
P. Pelicci
,
M. Lazar
Molecular and Cellular Biology
1998
Corpus ID: 24274830
ABSTRACT Nuclear receptor corepressor (CoR)-histone deacetylase (HDAC) complex recruitment is indispensable for the biological…
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Highly Cited
1996
Highly Cited
1996
HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription.
S. Rundlett
,
A. A. Carmen
,
R. Kobayashi
,
S. Bavykin
,
B. Turner
,
M. Grunstein
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 21893984
Increased histone acetylation has been correlated with increased transcription, and regions of heterochromatin are generally…
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